Dexmedetomidine as a novel therapeutic for postoperative pain in a patient treated with buprenorphine

Chad M. Brummett, Kavita A. Trivedi, Anna V. Dubovoy, Daniel W. Berland

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Buprenorphine is a partial agonist/antagonist used for the outpatient management of pain and addiction. It avidly binds to the opioid receptors and has a long and varied half-life. Its effects can impair the efficacy of opioids used for postoperative pain. The authors present a case of a patient managed with buprenorphine as an outpatient who presented for revision spine surgery and had significant postoperative pain that was successfully treated with hydromorphone and dexmedetomidine. This is the first reported use of dexmedetomidine for postoperative pain in a patient treated with buprenorphine.

Original languageEnglish (US)
Pages (from-to)175-179
Number of pages5
JournalJournal of Opioid Management
Volume5
Issue number3
StatePublished - May 2009

Fingerprint

Dexmedetomidine
Buprenorphine
Postoperative Pain
Outpatients
Hydromorphone
Opioid Receptors
Pain Management
Reoperation
Opioid Analgesics
Half-Life
Spine
Therapeutics

Keywords

  • Opioid
  • Precedex
  • Suboxone
  • Subutex

ASJC Scopus subject areas

  • Pharmacology (medical)
  • Anesthesiology and Pain Medicine

Cite this

Dexmedetomidine as a novel therapeutic for postoperative pain in a patient treated with buprenorphine. / Brummett, Chad M.; Trivedi, Kavita A.; Dubovoy, Anna V.; Berland, Daniel W.

In: Journal of Opioid Management, Vol. 5, No. 3, 05.2009, p. 175-179.

Research output: Contribution to journalArticle

Brummett, Chad M. ; Trivedi, Kavita A. ; Dubovoy, Anna V. ; Berland, Daniel W. / Dexmedetomidine as a novel therapeutic for postoperative pain in a patient treated with buprenorphine. In: Journal of Opioid Management. 2009 ; Vol. 5, No. 3. pp. 175-179.
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