Dexmedetomidine as sole sedative for awake intubation in management of the critical airway

Basem Abdelmalak, Laila Makary, Jeremy Hoban, D. John Doyle

Research output: Contribution to journalArticle

86 Citations (Scopus)

Abstract

We report a series of successful awake fiberoptic intubations in patients with critical (unstable, difficult) airways using the α2-agonist, dexmedetomidine. Dexmedetomidine has several desirable pharmacologic properties, including sedation, anxiolysis, hypnosis, analgesia, amnesia, antisialagogue effects, and a unique respiratory-sparing effect. Dexmedetomidine appears to be a useful agent for sedation during awake fiberoptic intubation in difficult airway patients.

Original languageEnglish (US)
Pages (from-to)370-373
Number of pages4
JournalJournal of Clinical Anesthesia
Volume19
Issue number5
DOIs
StatePublished - Aug 2007

Fingerprint

Dexmedetomidine
Airway Management
Hypnotics and Sedatives
Intubation
Amnesia
Hypnosis
Analgesia

Keywords

  • Awake intubation
  • Dexmedetomidine
  • Difficult airway
  • Fiberoptic bronchoscopy
  • Sedation

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine

Cite this

Dexmedetomidine as sole sedative for awake intubation in management of the critical airway. / Abdelmalak, Basem; Makary, Laila; Hoban, Jeremy; Doyle, D. John.

In: Journal of Clinical Anesthesia, Vol. 19, No. 5, 08.2007, p. 370-373.

Research output: Contribution to journalArticle

Abdelmalak, Basem ; Makary, Laila ; Hoban, Jeremy ; Doyle, D. John. / Dexmedetomidine as sole sedative for awake intubation in management of the critical airway. In: Journal of Clinical Anesthesia. 2007 ; Vol. 19, No. 5. pp. 370-373.
@article{85da2a09f4ad44649b64a1c7de6f6998,
title = "Dexmedetomidine as sole sedative for awake intubation in management of the critical airway",
abstract = "We report a series of successful awake fiberoptic intubations in patients with critical (unstable, difficult) airways using the α2-agonist, dexmedetomidine. Dexmedetomidine has several desirable pharmacologic properties, including sedation, anxiolysis, hypnosis, analgesia, amnesia, antisialagogue effects, and a unique respiratory-sparing effect. Dexmedetomidine appears to be a useful agent for sedation during awake fiberoptic intubation in difficult airway patients.",
keywords = "Awake intubation, Dexmedetomidine, Difficult airway, Fiberoptic bronchoscopy, Sedation",
author = "Basem Abdelmalak and Laila Makary and Jeremy Hoban and Doyle, {D. John}",
year = "2007",
month = "8",
doi = "10.1016/j.jclinane.2006.09.006",
language = "English (US)",
volume = "19",
pages = "370--373",
journal = "Journal of Clinical Anesthesia",
issn = "0952-8180",
publisher = "Elsevier Inc.",
number = "5",

}

TY - JOUR

T1 - Dexmedetomidine as sole sedative for awake intubation in management of the critical airway

AU - Abdelmalak, Basem

AU - Makary, Laila

AU - Hoban, Jeremy

AU - Doyle, D. John

PY - 2007/8

Y1 - 2007/8

N2 - We report a series of successful awake fiberoptic intubations in patients with critical (unstable, difficult) airways using the α2-agonist, dexmedetomidine. Dexmedetomidine has several desirable pharmacologic properties, including sedation, anxiolysis, hypnosis, analgesia, amnesia, antisialagogue effects, and a unique respiratory-sparing effect. Dexmedetomidine appears to be a useful agent for sedation during awake fiberoptic intubation in difficult airway patients.

AB - We report a series of successful awake fiberoptic intubations in patients with critical (unstable, difficult) airways using the α2-agonist, dexmedetomidine. Dexmedetomidine has several desirable pharmacologic properties, including sedation, anxiolysis, hypnosis, analgesia, amnesia, antisialagogue effects, and a unique respiratory-sparing effect. Dexmedetomidine appears to be a useful agent for sedation during awake fiberoptic intubation in difficult airway patients.

KW - Awake intubation

KW - Dexmedetomidine

KW - Difficult airway

KW - Fiberoptic bronchoscopy

KW - Sedation

UR - http://www.scopus.com/inward/record.url?scp=34548498412&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=34548498412&partnerID=8YFLogxK

U2 - 10.1016/j.jclinane.2006.09.006

DO - 10.1016/j.jclinane.2006.09.006

M3 - Article

C2 - 17869990

AN - SCOPUS:34548498412

VL - 19

SP - 370

EP - 373

JO - Journal of Clinical Anesthesia

JF - Journal of Clinical Anesthesia

SN - 0952-8180

IS - 5

ER -