Dexmedetomidine as sole sedative for awake intubation in management of the critical airway

Basem Abdelmalak, Laila Makary, Jeremy Hoban, D. John Doyle

Research output: Contribution to journalArticle

90 Scopus citations


We report a series of successful awake fiberoptic intubations in patients with critical (unstable, difficult) airways using the α2-agonist, dexmedetomidine. Dexmedetomidine has several desirable pharmacologic properties, including sedation, anxiolysis, hypnosis, analgesia, amnesia, antisialagogue effects, and a unique respiratory-sparing effect. Dexmedetomidine appears to be a useful agent for sedation during awake fiberoptic intubation in difficult airway patients.

Original languageEnglish (US)
Pages (from-to)370-373
Number of pages4
JournalJournal of Clinical Anesthesia
Issue number5
StatePublished - Aug 1 2007



  • Awake intubation
  • Dexmedetomidine
  • Difficult airway
  • Fiberoptic bronchoscopy
  • Sedation

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine

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