Diagnosis and management of ischemic colitis

Research output: Contribution to journalReview articlepeer-review

52 Scopus citations

Abstract

The clinical presentation and outcome of ischemic colitis has a wide spectrum. Impaired perfusion of blood to the bowel from a variety of causes is the underlying pathophysiology. The presence of diarrhea, abdominal pain, and mild lower gastrointestinal bleeding should prompt consideration of ischemic colitis as a cause. Although many laboratory tests and radiographic images may suggest the diagnosis, endoscopic visualization of colonic mucosa with histologic analysis of biopsies is the gold standard for identification of colonic ischemia. Most cases are transient and resolve without any complications. Medical therapy for chronic ischemia has been anecdotally proven but not carefully studied. Complications of ischemic colitis can include bowel perforation, peritonitis, persistent bleeding, protein-losing colopathy, and symptomatic intestinal strictures. Thus, surgical resection of the affected segment should be considered early to minimize adverse outcomes. This review describes the etiology, pathophysiology, clinical features, diagnostic approach, and management of ischemic colitis.

Original languageEnglish (US)
Pages (from-to)421-426
Number of pages6
JournalCurrent Gastroenterology Reports
Volume7
Issue number5
DOIs
StatePublished - Oct 2005

ASJC Scopus subject areas

  • Gastroenterology

Fingerprint Dive into the research topics of 'Diagnosis and management of ischemic colitis'. Together they form a unique fingerprint.

Cite this