Diagnostic utility and clinical significance of naso- and oropharyngeal samples used in a PCR assay to diagnose Mycoplasma pneumoniae infection in children with community-acquired pneumonia

Ian C. Michelow, Kurt Olsen, Juanita Lozano, Lynn B. Duffy, George H. McCracken, R. Doug Hardy

Research output: Contribution to journalArticle

47 Scopus citations

Abstract

PCR assays of naso- and oropharyngeal samples among hospitalized children appear equally effective for the diagnosis of serologically confirmed community-acquired mycoplasmal pneumonia. However, the combination of results from both sites yields optimal sensitivity (57%), specificity (98%), and positive (92%) and negative (82%) predictive values when compared with Mycoplasma pneumoniae enzyme-linked immunosorbent assay.

Original languageEnglish (US)
Pages (from-to)3339-3341
Number of pages3
JournalJournal of clinical microbiology
Volume42
Issue number7
DOIs
StatePublished - Jul 2004

ASJC Scopus subject areas

  • Microbiology (medical)

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