Abstract
Purpose: To investigate the diagnostic value of quantitative contrast-enhanced ultrasound (CEUS) for early detection of renal hyperperfusion in diabetic kidney disease (DKD). Materials and methods: 55 DKD patients with estimated glomerular filtration rate (eGFR) >30 ml/min/1.73 m2 and 26 normal controls (NCs) were enrolled. Clinical data was well documented. Blood samples were drawn for evaluation of renal function including blood urea nitrogen (BUN), serum creatinine (SCr) and serum uric acid (SUA), and urine samples were assayed for total protein quantification, and various microprotein markers. According to eGFR level, DKD patients were divided into early-stage DKD (eGFR ≥90 ml/min/1.73 m2, n = 18) and middle-stage DKD (eGFR 30–90 ml/min/1.73 m2, n = 37). Based on urinary microalbumin/creatinine ratio (MALB/UCR), early-stage DKD patients were further classified into two groups: MALB/UCR
| Original language | English (US) |
|---|---|
| Pages (from-to) | 669-678 |
| Number of pages | 10 |
| Journal | Journal of Nephrology |
| Volume | 28 |
| Issue number | 6 |
| DOIs | |
| State | Published - Dec 1 2015 |
Fingerprint
Keywords
- Contrast-enhanced ultrasound
- Diabetic kidney disease
- Renal perfusion
ASJC Scopus subject areas
- Nephrology
Cite this
Diagnostic value of quantitative contrast-enhanced ultrasound (CEUS) for early detection of renal hyperperfusion in diabetic kidney disease. / Wang, Ling; Wu, Jian; Cheng, Jia Fen; Liu, Xin Ying; Ma, Fang; Guo, Le Hang; Xu, Jun Mei; Wu, Tianfu; Mohan, Chandra; Peng, Ai; Xu, Hui Xiong; Song, Ya Xiang.
In: Journal of Nephrology, Vol. 28, No. 6, 01.12.2015, p. 669-678.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Diagnostic value of quantitative contrast-enhanced ultrasound (CEUS) for early detection of renal hyperperfusion in diabetic kidney disease
AU - Wang, Ling
AU - Wu, Jian
AU - Cheng, Jia Fen
AU - Liu, Xin Ying
AU - Ma, Fang
AU - Guo, Le Hang
AU - Xu, Jun Mei
AU - Wu, Tianfu
AU - Mohan, Chandra
AU - Peng, Ai
AU - Xu, Hui Xiong
AU - Song, Ya Xiang
PY - 2015/12/1
Y1 - 2015/12/1
N2 - Purpose: To investigate the diagnostic value of quantitative contrast-enhanced ultrasound (CEUS) for early detection of renal hyperperfusion in diabetic kidney disease (DKD). Materials and methods: 55 DKD patients with estimated glomerular filtration rate (eGFR) >30 ml/min/1.73 m2 and 26 normal controls (NCs) were enrolled. Clinical data was well documented. Blood samples were drawn for evaluation of renal function including blood urea nitrogen (BUN), serum creatinine (SCr) and serum uric acid (SUA), and urine samples were assayed for total protein quantification, and various microprotein markers. According to eGFR level, DKD patients were divided into early-stage DKD (eGFR ≥90 ml/min/1.73 m2, n = 18) and middle-stage DKD (eGFR 30–90 ml/min/1.73 m2, n = 37). Based on urinary microalbumin/creatinine ratio (MALB/UCR), early-stage DKD patients were further classified into two groups: MALB/UCR
AB - Purpose: To investigate the diagnostic value of quantitative contrast-enhanced ultrasound (CEUS) for early detection of renal hyperperfusion in diabetic kidney disease (DKD). Materials and methods: 55 DKD patients with estimated glomerular filtration rate (eGFR) >30 ml/min/1.73 m2 and 26 normal controls (NCs) were enrolled. Clinical data was well documented. Blood samples were drawn for evaluation of renal function including blood urea nitrogen (BUN), serum creatinine (SCr) and serum uric acid (SUA), and urine samples were assayed for total protein quantification, and various microprotein markers. According to eGFR level, DKD patients were divided into early-stage DKD (eGFR ≥90 ml/min/1.73 m2, n = 18) and middle-stage DKD (eGFR 30–90 ml/min/1.73 m2, n = 37). Based on urinary microalbumin/creatinine ratio (MALB/UCR), early-stage DKD patients were further classified into two groups: MALB/UCR
KW - Contrast-enhanced ultrasound
KW - Diabetic kidney disease
KW - Renal perfusion
UR - http://www.scopus.com/inward/record.url?scp=84944243041&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84944243041&partnerID=8YFLogxK
U2 - 10.1007/s40620-015-0183-3
DO - 10.1007/s40620-015-0183-3
M3 - Article
C2 - 25712236
AN - SCOPUS:84944243041
VL - 28
SP - 669
EP - 678
JO - Journal of Nephrology
JF - Journal of Nephrology
SN - 1121-8428
IS - 6
ER -