Diagnostic value of quantitative contrast-enhanced ultrasound (CEUS) for early detection of renal hyperperfusion in diabetic kidney disease

Ling Wang, Jian Wu, Jia Fen Cheng, Xin Ying Liu, Fang Ma, Le Hang Guo, Jun Mei Xu, Tianfu Wu, Chandra Mohan, Ai Peng, Hui Xiong Xu, Ya Xiang Song

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Purpose: To investigate the diagnostic value of quantitative contrast-enhanced ultrasound (CEUS) for early detection of renal hyperperfusion in diabetic kidney disease (DKD). Materials and methods: 55 DKD patients with estimated glomerular filtration rate (eGFR) >30 ml/min/1.73 m2 and 26 normal controls (NCs) were enrolled. Clinical data was well documented. Blood samples were drawn for evaluation of renal function including blood urea nitrogen (BUN), serum creatinine (SCr) and serum uric acid (SUA), and urine samples were assayed for total protein quantification, and various microprotein markers. According to eGFR level, DKD patients were divided into early-stage DKD (eGFR ≥90 ml/min/1.73 m2, n = 18) and middle-stage DKD (eGFR 30–90 ml/min/1.73 m2, n = 37). Based on urinary microalbumin/creatinine ratio (MALB/UCR), early-stage DKD patients were further classified into two groups: MALB/UCR

Original languageEnglish (US)
Pages (from-to)669-678
Number of pages10
JournalJournal of Nephrology
Volume28
Issue number6
DOIs
StatePublished - Dec 1 2015

Fingerprint

Diabetic Nephropathies
Glomerular Filtration Rate
Kidney
Creatinine
Blood Urea Nitrogen
Uric Acid
Serum
Urine
Proteins

Keywords

  • Contrast-enhanced ultrasound
  • Diabetic kidney disease
  • Renal perfusion

ASJC Scopus subject areas

  • Nephrology

Cite this

Diagnostic value of quantitative contrast-enhanced ultrasound (CEUS) for early detection of renal hyperperfusion in diabetic kidney disease. / Wang, Ling; Wu, Jian; Cheng, Jia Fen; Liu, Xin Ying; Ma, Fang; Guo, Le Hang; Xu, Jun Mei; Wu, Tianfu; Mohan, Chandra; Peng, Ai; Xu, Hui Xiong; Song, Ya Xiang.

In: Journal of Nephrology, Vol. 28, No. 6, 01.12.2015, p. 669-678.

Research output: Contribution to journalArticle

Wang, L, Wu, J, Cheng, JF, Liu, XY, Ma, F, Guo, LH, Xu, JM, Wu, T, Mohan, C, Peng, A, Xu, HX & Song, YX 2015, 'Diagnostic value of quantitative contrast-enhanced ultrasound (CEUS) for early detection of renal hyperperfusion in diabetic kidney disease', Journal of Nephrology, vol. 28, no. 6, pp. 669-678. https://doi.org/10.1007/s40620-015-0183-3
Wang, Ling ; Wu, Jian ; Cheng, Jia Fen ; Liu, Xin Ying ; Ma, Fang ; Guo, Le Hang ; Xu, Jun Mei ; Wu, Tianfu ; Mohan, Chandra ; Peng, Ai ; Xu, Hui Xiong ; Song, Ya Xiang. / Diagnostic value of quantitative contrast-enhanced ultrasound (CEUS) for early detection of renal hyperperfusion in diabetic kidney disease. In: Journal of Nephrology. 2015 ; Vol. 28, No. 6. pp. 669-678.
@article{77e36dbad0a143b2b196995fe572a994,
title = "Diagnostic value of quantitative contrast-enhanced ultrasound (CEUS) for early detection of renal hyperperfusion in diabetic kidney disease",
abstract = "Purpose: To investigate the diagnostic value of quantitative contrast-enhanced ultrasound (CEUS) for early detection of renal hyperperfusion in diabetic kidney disease (DKD). Materials and methods: 55 DKD patients with estimated glomerular filtration rate (eGFR) >30 ml/min/1.73 m2 and 26 normal controls (NCs) were enrolled. Clinical data was well documented. Blood samples were drawn for evaluation of renal function including blood urea nitrogen (BUN), serum creatinine (SCr) and serum uric acid (SUA), and urine samples were assayed for total protein quantification, and various microprotein markers. According to eGFR level, DKD patients were divided into early-stage DKD (eGFR ≥90 ml/min/1.73 m2, n = 18) and middle-stage DKD (eGFR 30–90 ml/min/1.73 m2, n = 37). Based on urinary microalbumin/creatinine ratio (MALB/UCR), early-stage DKD patients were further classified into two groups: MALB/UCR",
keywords = "Contrast-enhanced ultrasound, Diabetic kidney disease, Renal perfusion",
author = "Ling Wang and Jian Wu and Cheng, {Jia Fen} and Liu, {Xin Ying} and Fang Ma and Guo, {Le Hang} and Xu, {Jun Mei} and Tianfu Wu and Chandra Mohan and Ai Peng and Xu, {Hui Xiong} and Song, {Ya Xiang}",
year = "2015",
month = "12",
day = "1",
doi = "10.1007/s40620-015-0183-3",
language = "English (US)",
volume = "28",
pages = "669--678",
journal = "Journal of Nephrology",
issn = "1121-8428",
publisher = "Wichtig Publishing",
number = "6",

}

TY - JOUR

T1 - Diagnostic value of quantitative contrast-enhanced ultrasound (CEUS) for early detection of renal hyperperfusion in diabetic kidney disease

AU - Wang, Ling

AU - Wu, Jian

AU - Cheng, Jia Fen

AU - Liu, Xin Ying

AU - Ma, Fang

AU - Guo, Le Hang

AU - Xu, Jun Mei

AU - Wu, Tianfu

AU - Mohan, Chandra

AU - Peng, Ai

AU - Xu, Hui Xiong

AU - Song, Ya Xiang

PY - 2015/12/1

Y1 - 2015/12/1

N2 - Purpose: To investigate the diagnostic value of quantitative contrast-enhanced ultrasound (CEUS) for early detection of renal hyperperfusion in diabetic kidney disease (DKD). Materials and methods: 55 DKD patients with estimated glomerular filtration rate (eGFR) >30 ml/min/1.73 m2 and 26 normal controls (NCs) were enrolled. Clinical data was well documented. Blood samples were drawn for evaluation of renal function including blood urea nitrogen (BUN), serum creatinine (SCr) and serum uric acid (SUA), and urine samples were assayed for total protein quantification, and various microprotein markers. According to eGFR level, DKD patients were divided into early-stage DKD (eGFR ≥90 ml/min/1.73 m2, n = 18) and middle-stage DKD (eGFR 30–90 ml/min/1.73 m2, n = 37). Based on urinary microalbumin/creatinine ratio (MALB/UCR), early-stage DKD patients were further classified into two groups: MALB/UCR

AB - Purpose: To investigate the diagnostic value of quantitative contrast-enhanced ultrasound (CEUS) for early detection of renal hyperperfusion in diabetic kidney disease (DKD). Materials and methods: 55 DKD patients with estimated glomerular filtration rate (eGFR) >30 ml/min/1.73 m2 and 26 normal controls (NCs) were enrolled. Clinical data was well documented. Blood samples were drawn for evaluation of renal function including blood urea nitrogen (BUN), serum creatinine (SCr) and serum uric acid (SUA), and urine samples were assayed for total protein quantification, and various microprotein markers. According to eGFR level, DKD patients were divided into early-stage DKD (eGFR ≥90 ml/min/1.73 m2, n = 18) and middle-stage DKD (eGFR 30–90 ml/min/1.73 m2, n = 37). Based on urinary microalbumin/creatinine ratio (MALB/UCR), early-stage DKD patients were further classified into two groups: MALB/UCR

KW - Contrast-enhanced ultrasound

KW - Diabetic kidney disease

KW - Renal perfusion

UR - http://www.scopus.com/inward/record.url?scp=84944243041&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84944243041&partnerID=8YFLogxK

U2 - 10.1007/s40620-015-0183-3

DO - 10.1007/s40620-015-0183-3

M3 - Article

C2 - 25712236

AN - SCOPUS:84944243041

VL - 28

SP - 669

EP - 678

JO - Journal of Nephrology

JF - Journal of Nephrology

SN - 1121-8428

IS - 6

ER -