Diet and coronary heart disease

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

We might consider the use of diet in the therapy of hypercholesterolemia. Alteration of diet can produce a significant reduction of plasma cholesterol. Through the use of strict dietary alterations - decreasing saturated fats and cholesterol and increasing polyunsaturated fats - it should be possible to achieve a reduction in plasma cholesterol of about 30 to 40 mg/dl. In patients with mild hypercholesterolemia, say with a total cholesterol of 250 mg/dl, a decrease in plasma cholesterol of this magnitude would probably be adequate. On the other hand, if the plasma concentration is markedly elevated (e.g., over 300 mg/dl), dietary therapy alone is usually inadequate to reduce cholesterol satisfactorily, and strong consideration must be given to the use of drugs to achieve a normalization of the plasma cholesterol.

Original languageEnglish (US)
Pages (from-to)28-34
Number of pages7
JournalComprehensive Therapy
Volume6
Issue number11
StatePublished - 1980

Fingerprint

Coronary Disease
Cholesterol
Diet
Hypercholesterolemia
Fats
Diet Therapy
Pharmaceutical Preparations

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Diet and coronary heart disease. / Grundy, S. M.

In: Comprehensive Therapy, Vol. 6, No. 11, 1980, p. 28-34.

Research output: Contribution to journalArticle

Grundy, S. M. / Diet and coronary heart disease. In: Comprehensive Therapy. 1980 ; Vol. 6, No. 11. pp. 28-34.
@article{1f3ecece8bdb4befab8b9f5dbacf4555,
title = "Diet and coronary heart disease",
abstract = "We might consider the use of diet in the therapy of hypercholesterolemia. Alteration of diet can produce a significant reduction of plasma cholesterol. Through the use of strict dietary alterations - decreasing saturated fats and cholesterol and increasing polyunsaturated fats - it should be possible to achieve a reduction in plasma cholesterol of about 30 to 40 mg/dl. In patients with mild hypercholesterolemia, say with a total cholesterol of 250 mg/dl, a decrease in plasma cholesterol of this magnitude would probably be adequate. On the other hand, if the plasma concentration is markedly elevated (e.g., over 300 mg/dl), dietary therapy alone is usually inadequate to reduce cholesterol satisfactorily, and strong consideration must be given to the use of drugs to achieve a normalization of the plasma cholesterol.",
author = "Grundy, {S. M.}",
year = "1980",
language = "English (US)",
volume = "6",
pages = "28--34",
journal = "Comprehensive Therapy",
issn = "0098-8243",
publisher = "Humana Press",
number = "11",

}

TY - JOUR

T1 - Diet and coronary heart disease

AU - Grundy, S. M.

PY - 1980

Y1 - 1980

N2 - We might consider the use of diet in the therapy of hypercholesterolemia. Alteration of diet can produce a significant reduction of plasma cholesterol. Through the use of strict dietary alterations - decreasing saturated fats and cholesterol and increasing polyunsaturated fats - it should be possible to achieve a reduction in plasma cholesterol of about 30 to 40 mg/dl. In patients with mild hypercholesterolemia, say with a total cholesterol of 250 mg/dl, a decrease in plasma cholesterol of this magnitude would probably be adequate. On the other hand, if the plasma concentration is markedly elevated (e.g., over 300 mg/dl), dietary therapy alone is usually inadequate to reduce cholesterol satisfactorily, and strong consideration must be given to the use of drugs to achieve a normalization of the plasma cholesterol.

AB - We might consider the use of diet in the therapy of hypercholesterolemia. Alteration of diet can produce a significant reduction of plasma cholesterol. Through the use of strict dietary alterations - decreasing saturated fats and cholesterol and increasing polyunsaturated fats - it should be possible to achieve a reduction in plasma cholesterol of about 30 to 40 mg/dl. In patients with mild hypercholesterolemia, say with a total cholesterol of 250 mg/dl, a decrease in plasma cholesterol of this magnitude would probably be adequate. On the other hand, if the plasma concentration is markedly elevated (e.g., over 300 mg/dl), dietary therapy alone is usually inadequate to reduce cholesterol satisfactorily, and strong consideration must be given to the use of drugs to achieve a normalization of the plasma cholesterol.

UR - http://www.scopus.com/inward/record.url?scp=0019274698&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0019274698&partnerID=8YFLogxK

M3 - Article

VL - 6

SP - 28

EP - 34

JO - Comprehensive Therapy

JF - Comprehensive Therapy

SN - 0098-8243

IS - 11

ER -