Dietary Patterns and Long-Term Survival: A Retrospective Study of Healthy Primary Care Patients

Nilay S. Shah, David Leonard, Carrie E. Finley, Fatima Rodriguez, Ashish Sarraju, Carolyn E. Barlow, Laura F. DeFina, Benjamin L. Willis, William L. Haskell, David J. Maron

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Background: Dietary patterns are related to mortality in selected populations with comorbidities. We studied whether dietary patterns are associated with long-term survival in a middle-aged, healthy population. Methods: In this observational cohort study at the Cooper Clinic preventive medicine center (Dallas, Tex), a volunteer sample of 11,376 men and women with no history of myocardial infarction or stroke completed a baseline dietary assessment between 1987 and 1999 and were observed for an average of 18 years. Proportional hazard regressions, including a tree-augmented model, were used to assess the association of the Dietary Approaches to Stop Hypertension (DASH) dietary pattern, Mediterranean dietary pattern, and individual dietary components with mortality. The primary outcome was all-cause mortality. The secondary outcome was cardiovascular mortality. Results: Mean baseline age was 47 years. Each quintile increase in the DASH diet score was associated with a 6% lower adjusted risk for all-cause mortality (P < .02). The Mediterranean diet was not independently associated with all-cause or cardiovascular mortality. Solid fats and added sugars were the most predictive of mortality. Individuals who consumed >34% of their daily calories as solid fats had the highest risk for all-cause mortality. Conclusions: The DASH dietary pattern was associated with significantly lower all-cause mortality over approximately 2 decades of follow-up in a middle-aged, generally healthy population. Added solid fat and added sugar intake were the most predictive of all-cause mortality. These results suggest that promotion of a healthy dietary pattern should begin in middle age, before the development of comorbid risk factors.

Original languageEnglish (US)
JournalAmerican Journal of Medicine
DOIs
StateAccepted/In press - 2017

Fingerprint

Primary Health Care
Retrospective Studies
Survival
Mortality
Hypertension
Fats
Population
Preventive Medicine
Observational Studies
Comorbidity
Volunteers
Cohort Studies
Stroke
Myocardial Infarction
Diet

Keywords

  • Cardiovascular disease mortality
  • Dietary intake
  • Dietary patterns
  • Mortality

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Shah, N. S., Leonard, D., Finley, C. E., Rodriguez, F., Sarraju, A., Barlow, C. E., ... Maron, D. J. (Accepted/In press). Dietary Patterns and Long-Term Survival: A Retrospective Study of Healthy Primary Care Patients. American Journal of Medicine. https://doi.org/10.1016/j.amjmed.2017.08.010

Dietary Patterns and Long-Term Survival : A Retrospective Study of Healthy Primary Care Patients. / Shah, Nilay S.; Leonard, David; Finley, Carrie E.; Rodriguez, Fatima; Sarraju, Ashish; Barlow, Carolyn E.; DeFina, Laura F.; Willis, Benjamin L.; Haskell, William L.; Maron, David J.

In: American Journal of Medicine, 2017.

Research output: Contribution to journalArticle

Shah, NS, Leonard, D, Finley, CE, Rodriguez, F, Sarraju, A, Barlow, CE, DeFina, LF, Willis, BL, Haskell, WL & Maron, DJ 2017, 'Dietary Patterns and Long-Term Survival: A Retrospective Study of Healthy Primary Care Patients', American Journal of Medicine. https://doi.org/10.1016/j.amjmed.2017.08.010
Shah, Nilay S. ; Leonard, David ; Finley, Carrie E. ; Rodriguez, Fatima ; Sarraju, Ashish ; Barlow, Carolyn E. ; DeFina, Laura F. ; Willis, Benjamin L. ; Haskell, William L. ; Maron, David J. / Dietary Patterns and Long-Term Survival : A Retrospective Study of Healthy Primary Care Patients. In: American Journal of Medicine. 2017.
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abstract = "Background: Dietary patterns are related to mortality in selected populations with comorbidities. We studied whether dietary patterns are associated with long-term survival in a middle-aged, healthy population. Methods: In this observational cohort study at the Cooper Clinic preventive medicine center (Dallas, Tex), a volunteer sample of 11,376 men and women with no history of myocardial infarction or stroke completed a baseline dietary assessment between 1987 and 1999 and were observed for an average of 18 years. Proportional hazard regressions, including a tree-augmented model, were used to assess the association of the Dietary Approaches to Stop Hypertension (DASH) dietary pattern, Mediterranean dietary pattern, and individual dietary components with mortality. The primary outcome was all-cause mortality. The secondary outcome was cardiovascular mortality. Results: Mean baseline age was 47 years. Each quintile increase in the DASH diet score was associated with a 6{\%} lower adjusted risk for all-cause mortality (P < .02). The Mediterranean diet was not independently associated with all-cause or cardiovascular mortality. Solid fats and added sugars were the most predictive of mortality. Individuals who consumed >34{\%} of their daily calories as solid fats had the highest risk for all-cause mortality. Conclusions: The DASH dietary pattern was associated with significantly lower all-cause mortality over approximately 2 decades of follow-up in a middle-aged, generally healthy population. Added solid fat and added sugar intake were the most predictive of all-cause mortality. These results suggest that promotion of a healthy dietary pattern should begin in middle age, before the development of comorbid risk factors.",
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AU - Sarraju, Ashish

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N2 - Background: Dietary patterns are related to mortality in selected populations with comorbidities. We studied whether dietary patterns are associated with long-term survival in a middle-aged, healthy population. Methods: In this observational cohort study at the Cooper Clinic preventive medicine center (Dallas, Tex), a volunteer sample of 11,376 men and women with no history of myocardial infarction or stroke completed a baseline dietary assessment between 1987 and 1999 and were observed for an average of 18 years. Proportional hazard regressions, including a tree-augmented model, were used to assess the association of the Dietary Approaches to Stop Hypertension (DASH) dietary pattern, Mediterranean dietary pattern, and individual dietary components with mortality. The primary outcome was all-cause mortality. The secondary outcome was cardiovascular mortality. Results: Mean baseline age was 47 years. Each quintile increase in the DASH diet score was associated with a 6% lower adjusted risk for all-cause mortality (P < .02). The Mediterranean diet was not independently associated with all-cause or cardiovascular mortality. Solid fats and added sugars were the most predictive of mortality. Individuals who consumed >34% of their daily calories as solid fats had the highest risk for all-cause mortality. Conclusions: The DASH dietary pattern was associated with significantly lower all-cause mortality over approximately 2 decades of follow-up in a middle-aged, generally healthy population. Added solid fat and added sugar intake were the most predictive of all-cause mortality. These results suggest that promotion of a healthy dietary pattern should begin in middle age, before the development of comorbid risk factors.

AB - Background: Dietary patterns are related to mortality in selected populations with comorbidities. We studied whether dietary patterns are associated with long-term survival in a middle-aged, healthy population. Methods: In this observational cohort study at the Cooper Clinic preventive medicine center (Dallas, Tex), a volunteer sample of 11,376 men and women with no history of myocardial infarction or stroke completed a baseline dietary assessment between 1987 and 1999 and were observed for an average of 18 years. Proportional hazard regressions, including a tree-augmented model, were used to assess the association of the Dietary Approaches to Stop Hypertension (DASH) dietary pattern, Mediterranean dietary pattern, and individual dietary components with mortality. The primary outcome was all-cause mortality. The secondary outcome was cardiovascular mortality. Results: Mean baseline age was 47 years. Each quintile increase in the DASH diet score was associated with a 6% lower adjusted risk for all-cause mortality (P < .02). The Mediterranean diet was not independently associated with all-cause or cardiovascular mortality. Solid fats and added sugars were the most predictive of mortality. Individuals who consumed >34% of their daily calories as solid fats had the highest risk for all-cause mortality. Conclusions: The DASH dietary pattern was associated with significantly lower all-cause mortality over approximately 2 decades of follow-up in a middle-aged, generally healthy population. Added solid fat and added sugar intake were the most predictive of all-cause mortality. These results suggest that promotion of a healthy dietary pattern should begin in middle age, before the development of comorbid risk factors.

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