TY - JOUR
T1 - Differences in quality of life in patients with cutaneous lupus erythematosus with varying income levels
AU - Joseph, Adrienne
AU - Prasad, Smriti
AU - Hynan, Linda S.
AU - Chren, Mary Margaret
AU - Chong, Benjamin
N1 - Funding Information:
The authors would like to thank Rebecca Vasquez, Andrew Kim, Daniel Grabell, Noelle Teske, Tina Vinoya, Jack O’Brien, Elaine Kunzler, Stephanie Florez-Pollack, Jennifer Coias, Danielle Lin, Jenny Raman, and Justin Raman for recruiting patients. The authors would like to thank participants of the University of Texas Southwestern CLE Registry for their contributions to lupus research. The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: The research reported in this publication was supported by the National Institute of Arthritis and Musculoskeletal and Skin Diseases of the National Institutes of Health under Award Number K23AR0614415. The content is solely the responsibility of the authors and does not necessarily represent the official views of The University of Texas Southwestern Medical Center at Dallas and its affiliated academic and health care centers, the National Center for Research Resources, and the National Institutes of Health.
Funding Information:
The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: The research reported in this publication was supported by the National Institute of Arthritis and Musculoskeletal and Skin Diseases of the National Institutes of Health under Award Number K23AR0614415. The content is solely the responsibility of the authors and does not necessarily represent the official views of The University of Texas Southwestern Medical Center at Dallas and its affiliated academic and health care centers, the National Center for Research Resources, and the National Institutes of Health.
Publisher Copyright:
© The Author(s) 2021.
PY - 2021/5
Y1 - 2021/5
N2 - Background: Cutaneous lupus erythematosus (CLE) is an autoimmune photosensitive skin condition. The impact of income on quality of life has been incompletely characterized in CLE. Objectives: We aimed to assess how annual income affects quality of life among CLE patients. Methods: In this cross-sectional study of 238 patients with CLE, relationships between predictor variables including annual income and each SKINDEX-29 + 3 subdomain were identified using univariate and multivariable analyses. In addition, answers to individual SKINDEX-29 + 3 questions were compared across income groups. Clinical factors in patients making less than <10,000 USD (N = 85) with worse SKINDEX-29 + 3 scores were also identified by univariate and multivariable analyses. Results: Patients making <10,000 USD annually experienced worse quality of life across multiple SKINDEX-29 + 3 subdomains (p < 0.05). These patients specifically experienced poorer quality of life relating to social isolation and self-consciousness. (p < 0.001). Among those making <10,000 USD, predictors for worse quality of life included females, smokers, and those with higher skin disease activity were identified (p < 0.05). Limitations: This is a single center study. Income was also self-reported and could not be verified. Conclusions: Lower income is related to poorer quality of life in patients with CLE. Specifically, patients experience limitations regarding social isolation and self-consciousness.
AB - Background: Cutaneous lupus erythematosus (CLE) is an autoimmune photosensitive skin condition. The impact of income on quality of life has been incompletely characterized in CLE. Objectives: We aimed to assess how annual income affects quality of life among CLE patients. Methods: In this cross-sectional study of 238 patients with CLE, relationships between predictor variables including annual income and each SKINDEX-29 + 3 subdomain were identified using univariate and multivariable analyses. In addition, answers to individual SKINDEX-29 + 3 questions were compared across income groups. Clinical factors in patients making less than <10,000 USD (N = 85) with worse SKINDEX-29 + 3 scores were also identified by univariate and multivariable analyses. Results: Patients making <10,000 USD annually experienced worse quality of life across multiple SKINDEX-29 + 3 subdomains (p < 0.05). These patients specifically experienced poorer quality of life relating to social isolation and self-consciousness. (p < 0.001). Among those making <10,000 USD, predictors for worse quality of life included females, smokers, and those with higher skin disease activity were identified (p < 0.05). Limitations: This is a single center study. Income was also self-reported and could not be verified. Conclusions: Lower income is related to poorer quality of life in patients with CLE. Specifically, patients experience limitations regarding social isolation and self-consciousness.
KW - Quality of life
KW - SKINDEX-29
KW - autoimmune skin diseases
KW - cutaneous lupus erythematosus
KW - rheumatic diseases
KW - socioeconomic status
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U2 - 10.1177/0961203321999724
DO - 10.1177/0961203321999724
M3 - Article
C2 - 33663251
AN - SCOPUS:85102169208
SN - 0961-2033
VL - 30
SP - 972
EP - 980
JO - Lupus
JF - Lupus
IS - 6
ER -