@article{0e721c401f224ccb96f3a246e22f2eef,
title = "Different originating cells underlie intertumoral heterogeneity in lung neuroendocrine tumors",
abstract = "Studies in genetically engineered mouse models of neuroendocrine lung cancer suggest that differences in cells of origin underlie subtype variations in this class of cancers. These findings highlight the concept that the same driver mutations introduced into different cells of origin lead to tumors with the same histology but dramatically different metastatic programs and potentially different therapeutic responses.",
author = "Karine Pozo and Kelenis, {Demetra P.} and Minna, {John D.} and Johnson, {Jane E.}",
note = "Funding Information: K. Pozo, J.D. Minna, and J.E. Johnson are supported by National Cancer Institute Specialized Programs of Research Excellence (SPORE) in Lung Cancer P50CA70907, U01CA213338, and U24 CA213274. D.P. Kelenis is supported by the Cancer Prevention and Research Institute of Texas training grant RP160157. Publisher Copyright: {\textcopyright}2018 American Association for Cancer Research.",
year = "2018",
month = oct,
doi = "10.1158/2159-8290.CD-18-0979",
language = "English (US)",
volume = "8",
pages = "1216--1218",
journal = "Cancer Discovery",
issn = "2159-8274",
publisher = "American Association for Cancer Research Inc.",
number = "10",
}