Differential channeling of sensory stimuli onto a motor neuron in the leech

I. Iscla, P. D. Arini, L. Szczupak

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

We studied a specific sensory-motor pathway in the isolated leech ganglia. Pressure-sensitive mechanosensory neurons were stimulated with trains of action potentials at 5-20 Hz while recording the responses of the annulus erector motorneurons that control annuli erection. The response of the annulus erector neurons was a succession of excitatory postsynaptic potentials followed by inhibitory postsynaptic potentials. The excitatory postsynaptic potentials had a brief time-course while the inhibitory postsynaptic potentials had a prolonged time-course that enabled their temporal summation. Thus, the net effect of pressure-sensitive neuron stimulation on the annulus erector neurons was inhibitory. Both phases of the response were mediated by chemical transmission; the excitatory postsynaptic potentials were transmitted via a monosynaptic pathway, and the inhibitory postsynaptic potentials via a polysynaptic one. The pattern of expression of this dual response depended on the field of innervation of the sensory neuron and it was under the influence of cell 151, a non-spiking interneuron, that could regulate the expression of the hyperpolarization. The interaction between pressure-sensitive neurons and annulus erector neuron reveals how sensory specificity, connectivity pattern and regulatory elements interplay in a specific sensory-motor network.

Original languageEnglish (US)
Pages (from-to)233-241
Number of pages9
JournalJournal of Comparative Physiology - A Sensory, Neural, and Behavioral Physiology
Volume184
Issue number2
DOIs
StatePublished - Feb 1999

Fingerprint

Leeches
leech
Hirudinea
Motor Neurons
motor neurons
neurons
Inhibitory Postsynaptic Potentials
Excitatory Postsynaptic Potentials
Neurons
Sensory Receptor Cells
Pressure
train
connectivity
Efferent Pathways
Interneurons
Ganglia
sensory neurons
interneurons
Action Potentials
innervation

Keywords

  • Electric junction
  • Leech
  • Non-spiking interneuron
  • Sensory integration
  • Sensory-motor

ASJC Scopus subject areas

  • Animal Science and Zoology
  • Physiology
  • Physiology (medical)
  • Behavioral Neuroscience
  • Neuroscience(all)

Cite this

Differential channeling of sensory stimuli onto a motor neuron in the leech. / Iscla, I.; Arini, P. D.; Szczupak, L.

In: Journal of Comparative Physiology - A Sensory, Neural, and Behavioral Physiology, Vol. 184, No. 2, 02.1999, p. 233-241.

Research output: Contribution to journalArticle

@article{742c4b27676046609e343020a14b74f7,
title = "Differential channeling of sensory stimuli onto a motor neuron in the leech",
abstract = "We studied a specific sensory-motor pathway in the isolated leech ganglia. Pressure-sensitive mechanosensory neurons were stimulated with trains of action potentials at 5-20 Hz while recording the responses of the annulus erector motorneurons that control annuli erection. The response of the annulus erector neurons was a succession of excitatory postsynaptic potentials followed by inhibitory postsynaptic potentials. The excitatory postsynaptic potentials had a brief time-course while the inhibitory postsynaptic potentials had a prolonged time-course that enabled their temporal summation. Thus, the net effect of pressure-sensitive neuron stimulation on the annulus erector neurons was inhibitory. Both phases of the response were mediated by chemical transmission; the excitatory postsynaptic potentials were transmitted via a monosynaptic pathway, and the inhibitory postsynaptic potentials via a polysynaptic one. The pattern of expression of this dual response depended on the field of innervation of the sensory neuron and it was under the influence of cell 151, a non-spiking interneuron, that could regulate the expression of the hyperpolarization. The interaction between pressure-sensitive neurons and annulus erector neuron reveals how sensory specificity, connectivity pattern and regulatory elements interplay in a specific sensory-motor network.",
keywords = "Electric junction, Leech, Non-spiking interneuron, Sensory integration, Sensory-motor",
author = "I. Iscla and Arini, {P. D.} and L. Szczupak",
year = "1999",
month = "2",
doi = "10.1007/s003590050321",
language = "English (US)",
volume = "184",
pages = "233--241",
journal = "Journal of Comparative Physiology A: Neuroethology, Sensory, Neural, and Behavioral Physiology",
issn = "0340-7594",
publisher = "Springer Verlag",
number = "2",

}

TY - JOUR

T1 - Differential channeling of sensory stimuli onto a motor neuron in the leech

AU - Iscla, I.

AU - Arini, P. D.

AU - Szczupak, L.

PY - 1999/2

Y1 - 1999/2

N2 - We studied a specific sensory-motor pathway in the isolated leech ganglia. Pressure-sensitive mechanosensory neurons were stimulated with trains of action potentials at 5-20 Hz while recording the responses of the annulus erector motorneurons that control annuli erection. The response of the annulus erector neurons was a succession of excitatory postsynaptic potentials followed by inhibitory postsynaptic potentials. The excitatory postsynaptic potentials had a brief time-course while the inhibitory postsynaptic potentials had a prolonged time-course that enabled their temporal summation. Thus, the net effect of pressure-sensitive neuron stimulation on the annulus erector neurons was inhibitory. Both phases of the response were mediated by chemical transmission; the excitatory postsynaptic potentials were transmitted via a monosynaptic pathway, and the inhibitory postsynaptic potentials via a polysynaptic one. The pattern of expression of this dual response depended on the field of innervation of the sensory neuron and it was under the influence of cell 151, a non-spiking interneuron, that could regulate the expression of the hyperpolarization. The interaction between pressure-sensitive neurons and annulus erector neuron reveals how sensory specificity, connectivity pattern and regulatory elements interplay in a specific sensory-motor network.

AB - We studied a specific sensory-motor pathway in the isolated leech ganglia. Pressure-sensitive mechanosensory neurons were stimulated with trains of action potentials at 5-20 Hz while recording the responses of the annulus erector motorneurons that control annuli erection. The response of the annulus erector neurons was a succession of excitatory postsynaptic potentials followed by inhibitory postsynaptic potentials. The excitatory postsynaptic potentials had a brief time-course while the inhibitory postsynaptic potentials had a prolonged time-course that enabled their temporal summation. Thus, the net effect of pressure-sensitive neuron stimulation on the annulus erector neurons was inhibitory. Both phases of the response were mediated by chemical transmission; the excitatory postsynaptic potentials were transmitted via a monosynaptic pathway, and the inhibitory postsynaptic potentials via a polysynaptic one. The pattern of expression of this dual response depended on the field of innervation of the sensory neuron and it was under the influence of cell 151, a non-spiking interneuron, that could regulate the expression of the hyperpolarization. The interaction between pressure-sensitive neurons and annulus erector neuron reveals how sensory specificity, connectivity pattern and regulatory elements interplay in a specific sensory-motor network.

KW - Electric junction

KW - Leech

KW - Non-spiking interneuron

KW - Sensory integration

KW - Sensory-motor

UR - http://www.scopus.com/inward/record.url?scp=0033082310&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0033082310&partnerID=8YFLogxK

U2 - 10.1007/s003590050321

DO - 10.1007/s003590050321

M3 - Article

VL - 184

SP - 233

EP - 241

JO - Journal of Comparative Physiology A: Neuroethology, Sensory, Neural, and Behavioral Physiology

JF - Journal of Comparative Physiology A: Neuroethology, Sensory, Neural, and Behavioral Physiology

SN - 0340-7594

IS - 2

ER -