Diffuse optical tomography in the presence of a chest wall

Han Y. Ban, David R. Busch, Saurav Pathak, Frank A. Moscatelli, Manabu Machida, John C. Schotland, Vadim A. Markel, Arjun G. Yodh

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Diffuse optical tomography (DOT) has been employed to derive spatial maps of physiologically important chromophores in the human breast, but the fidelity of these images is often compromised by boundary effects such as those due to the chest wall. We explore the image quality in fast, data-intensive analytic and algebraic linear DOT reconstructions of phantoms with subcentimeter target features and large absorptive regions mimicking the chest wall. Experiments demonstrate that the chest wall phantom can introduce severe image artifacts. We then show how these artifacts can be mitigated by exclusion of data affected by the chest wall. We also introduce and demonstrate a linear algebraic reconstruction method well suited for very large data sets in the presence of a chest wall.

Original languageEnglish (US)
Article number026016
JournalJournal of biomedical optics
Volume18
Issue number2
DOIs
StatePublished - Feb 1 2013
Externally publishedYes

Fingerprint

chest
Optical tomography
tomography
Chromophores
Image quality
artifacts
exclusion
breast
Experiments
chromophores

Keywords

  • Image reconstruction
  • Imaging systems
  • Tomography

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Atomic and Molecular Physics, and Optics
  • Biomedical Engineering

Cite this

Ban, H. Y., Busch, D. R., Pathak, S., Moscatelli, F. A., Machida, M., Schotland, J. C., ... Yodh, A. G. (2013). Diffuse optical tomography in the presence of a chest wall. Journal of biomedical optics, 18(2), [026016]. https://doi.org/10.1117/1.JBO.18.2.026016

Diffuse optical tomography in the presence of a chest wall. / Ban, Han Y.; Busch, David R.; Pathak, Saurav; Moscatelli, Frank A.; Machida, Manabu; Schotland, John C.; Markel, Vadim A.; Yodh, Arjun G.

In: Journal of biomedical optics, Vol. 18, No. 2, 026016, 01.02.2013.

Research output: Contribution to journalArticle

Ban, HY, Busch, DR, Pathak, S, Moscatelli, FA, Machida, M, Schotland, JC, Markel, VA & Yodh, AG 2013, 'Diffuse optical tomography in the presence of a chest wall', Journal of biomedical optics, vol. 18, no. 2, 026016. https://doi.org/10.1117/1.JBO.18.2.026016
Ban HY, Busch DR, Pathak S, Moscatelli FA, Machida M, Schotland JC et al. Diffuse optical tomography in the presence of a chest wall. Journal of biomedical optics. 2013 Feb 1;18(2). 026016. https://doi.org/10.1117/1.JBO.18.2.026016
Ban, Han Y. ; Busch, David R. ; Pathak, Saurav ; Moscatelli, Frank A. ; Machida, Manabu ; Schotland, John C. ; Markel, Vadim A. ; Yodh, Arjun G. / Diffuse optical tomography in the presence of a chest wall. In: Journal of biomedical optics. 2013 ; Vol. 18, No. 2.
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