Lissencephaly is a rare brain malformation characterized histologically by arrested neuronal migration such that the brain resembles that of a fetus before 23-24 weeks gestation. We studied a neonate with lissencephaly by using diffusion tensor imaging and suggest the dysplastic densely cellular layer IV is visible as a band of anisotropic diffusion. Fiber tracking showed lack of connectivity between the cortex and deep white matter and an abnormal limbic system.
|Original language||English (US)|
|Number of pages||4|
|Journal||American Journal of Neuroradiology|
|State||Published - Dec 1 2005|
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging
- Clinical Neurology