Diffusion tensor imaging in lissencephaly

Nancy Rollins, Tony Reyes, Jon Chia

Research output: Contribution to journalArticle

24 Scopus citations

Abstract

Lissencephaly is a rare brain malformation characterized histologically by arrested neuronal migration such that the brain resembles that of a fetus before 23-24 weeks gestation. We studied a neonate with lissencephaly by using diffusion tensor imaging and suggest the dysplastic densely cellular layer IV is visible as a band of anisotropic diffusion. Fiber tracking showed lack of connectivity between the cortex and deep white matter and an abnormal limbic system.

Original languageEnglish (US)
Pages (from-to)1583-1586
Number of pages4
JournalAmerican Journal of Neuroradiology
Volume26
Issue number6
StatePublished - Dec 1 2005

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ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Clinical Neurology

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