Digital medicine program with pediatric solid organ transplant patients: Perceived benefits and challenges

Kelli Nicole Triplett, Ana F. El-Behadli, Saba S. Masood, Sarah Sullivan, Dev M Desai

Research output: Contribution to journalArticle

Abstract

Given the complexity of the pediatric post-transplant medication regimen and known medication adherence difficulties within the solid organ transplant population, interventions to improve adherence continue to be explored and fine-tuned. Advances in technology have led to the development of new programs aimed at improving medication adherence and the overall care of transplant patients. This manuscript describes implementation of a DMP where transplant patients' medications were co-encapsulated with ingestible sensors, and adherence was monitored via a patient mobile application and a provider portal. The benefits and challenges of the DMP as reported by patients, caregivers, and medical providers are explored in this manuscript. Participant feedback regarding best practices highlighted these benefits: ease of use/intuitive technology, sense of improved communication with medical team, increased knowledge and motivation around treatment regimen, and positive self-reports of medication adherence. Challenges included reluctance to participate (n = 43, 54.43% of patients approached declined participation) and patch wearability difficulties reported by participants (n = 20; 68.97%). Other notable challenges included the following: limited drug profile compatibility with the DMP technology and concerns about privacy and electronic data sharing for patients who chose not to participate. DMP implementation highlighted how technological advances offer novel methods to assess adherence, enhance medical decision-making, and can potentially improve clinical outcomes. Although numerous benefits of the program were recognized by participants, challenges were identified and the DMP technology and medication panel continues to be refined; further investigation of such programs continues to be warranted.

Original languageEnglish (US)
Article numbere13555
JournalPediatric Transplantation
DOIs
StatePublished - Jan 1 2019

Fingerprint

Medicine
Medication Adherence
Pediatrics
Transplants
Technology
Mobile Applications
Program Development
Information Dissemination
Privacy
Practice Guidelines
Self Report
Caregivers
Motivation
Patient Care
Communication
Pharmaceutical Preparations
Population
Therapeutics

Keywords

  • adolescence
  • computer applications/ehealth
  • technology
  • treatment adherence

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Transplantation

Cite this

Digital medicine program with pediatric solid organ transplant patients : Perceived benefits and challenges. / Triplett, Kelli Nicole; El-Behadli, Ana F.; Masood, Saba S.; Sullivan, Sarah; Desai, Dev M.

In: Pediatric Transplantation, 01.01.2019.

Research output: Contribution to journalArticle

@article{13521f4b5afe4245932e53ed7a5bc834,
title = "Digital medicine program with pediatric solid organ transplant patients: Perceived benefits and challenges",
abstract = "Given the complexity of the pediatric post-transplant medication regimen and known medication adherence difficulties within the solid organ transplant population, interventions to improve adherence continue to be explored and fine-tuned. Advances in technology have led to the development of new programs aimed at improving medication adherence and the overall care of transplant patients. This manuscript describes implementation of a DMP where transplant patients' medications were co-encapsulated with ingestible sensors, and adherence was monitored via a patient mobile application and a provider portal. The benefits and challenges of the DMP as reported by patients, caregivers, and medical providers are explored in this manuscript. Participant feedback regarding best practices highlighted these benefits: ease of use/intuitive technology, sense of improved communication with medical team, increased knowledge and motivation around treatment regimen, and positive self-reports of medication adherence. Challenges included reluctance to participate (n = 43, 54.43{\%} of patients approached declined participation) and patch wearability difficulties reported by participants (n = 20; 68.97{\%}). Other notable challenges included the following: limited drug profile compatibility with the DMP technology and concerns about privacy and electronic data sharing for patients who chose not to participate. DMP implementation highlighted how technological advances offer novel methods to assess adherence, enhance medical decision-making, and can potentially improve clinical outcomes. Although numerous benefits of the program were recognized by participants, challenges were identified and the DMP technology and medication panel continues to be refined; further investigation of such programs continues to be warranted.",
keywords = "adolescence, computer applications/ehealth, technology, treatment adherence",
author = "Triplett, {Kelli Nicole} and El-Behadli, {Ana F.} and Masood, {Saba S.} and Sarah Sullivan and Desai, {Dev M}",
year = "2019",
month = "1",
day = "1",
doi = "10.1111/petr.13555",
language = "English (US)",
journal = "Pediatric Transplantation",
issn = "1397-3142",
publisher = "Wiley-Blackwell",

}

TY - JOUR

T1 - Digital medicine program with pediatric solid organ transplant patients

T2 - Perceived benefits and challenges

AU - Triplett, Kelli Nicole

AU - El-Behadli, Ana F.

AU - Masood, Saba S.

AU - Sullivan, Sarah

AU - Desai, Dev M

PY - 2019/1/1

Y1 - 2019/1/1

N2 - Given the complexity of the pediatric post-transplant medication regimen and known medication adherence difficulties within the solid organ transplant population, interventions to improve adherence continue to be explored and fine-tuned. Advances in technology have led to the development of new programs aimed at improving medication adherence and the overall care of transplant patients. This manuscript describes implementation of a DMP where transplant patients' medications were co-encapsulated with ingestible sensors, and adherence was monitored via a patient mobile application and a provider portal. The benefits and challenges of the DMP as reported by patients, caregivers, and medical providers are explored in this manuscript. Participant feedback regarding best practices highlighted these benefits: ease of use/intuitive technology, sense of improved communication with medical team, increased knowledge and motivation around treatment regimen, and positive self-reports of medication adherence. Challenges included reluctance to participate (n = 43, 54.43% of patients approached declined participation) and patch wearability difficulties reported by participants (n = 20; 68.97%). Other notable challenges included the following: limited drug profile compatibility with the DMP technology and concerns about privacy and electronic data sharing for patients who chose not to participate. DMP implementation highlighted how technological advances offer novel methods to assess adherence, enhance medical decision-making, and can potentially improve clinical outcomes. Although numerous benefits of the program were recognized by participants, challenges were identified and the DMP technology and medication panel continues to be refined; further investigation of such programs continues to be warranted.

AB - Given the complexity of the pediatric post-transplant medication regimen and known medication adherence difficulties within the solid organ transplant population, interventions to improve adherence continue to be explored and fine-tuned. Advances in technology have led to the development of new programs aimed at improving medication adherence and the overall care of transplant patients. This manuscript describes implementation of a DMP where transplant patients' medications were co-encapsulated with ingestible sensors, and adherence was monitored via a patient mobile application and a provider portal. The benefits and challenges of the DMP as reported by patients, caregivers, and medical providers are explored in this manuscript. Participant feedback regarding best practices highlighted these benefits: ease of use/intuitive technology, sense of improved communication with medical team, increased knowledge and motivation around treatment regimen, and positive self-reports of medication adherence. Challenges included reluctance to participate (n = 43, 54.43% of patients approached declined participation) and patch wearability difficulties reported by participants (n = 20; 68.97%). Other notable challenges included the following: limited drug profile compatibility with the DMP technology and concerns about privacy and electronic data sharing for patients who chose not to participate. DMP implementation highlighted how technological advances offer novel methods to assess adherence, enhance medical decision-making, and can potentially improve clinical outcomes. Although numerous benefits of the program were recognized by participants, challenges were identified and the DMP technology and medication panel continues to be refined; further investigation of such programs continues to be warranted.

KW - adolescence

KW - computer applications/ehealth

KW - technology

KW - treatment adherence

UR - http://www.scopus.com/inward/record.url?scp=85069806191&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85069806191&partnerID=8YFLogxK

U2 - 10.1111/petr.13555

DO - 10.1111/petr.13555

M3 - Article

C2 - 31328842

AN - SCOPUS:85069806191

JO - Pediatric Transplantation

JF - Pediatric Transplantation

SN - 1397-3142

M1 - e13555

ER -