DILI: New insights into diagnosis and management

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Drug-induced liver injury continues to have a significant impact. With over 1000 drugs now registered as causing DILI, this form of liver injury is the most cited reason for withdrawal of a drug from the marketplace. Despite this, the diagnosis of DILI continues to rely on subjective measures and expert opinion with results that are both difficult to verify and reproduce. However, recent developments in DILI research may provide new insights to improve diagnosis and treatment in the future.

Original languageEnglish (US)
Pages (from-to)53-58
Number of pages6
JournalCurrent Hepatitis Reports
Volume12
Issue number1
DOIs
StatePublished - Mar 2013

Fingerprint

Chemical and Drug Induced Liver Injury
Expert Testimony
Pharmaceutical Preparations
Liver
Wounds and Injuries
Research

Keywords

  • Acetaminophen
  • Biotransformation
  • Genetic polymorphism
  • Genome wide association study
  • Herbal and dietary supplements

ASJC Scopus subject areas

  • Hepatology
  • Virology

Cite this

DILI : New insights into diagnosis and management. / Tran, Thanh; Lee, William M.

In: Current Hepatitis Reports, Vol. 12, No. 1, 03.2013, p. 53-58.

Research output: Contribution to journalArticle

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