Direct transfer of adult hookworms (Ancylostoma duodenale) from dog to child for therapeutic purposes

J. N. Walterspiel, G. A. Schad, G. R. Buchanan

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

To induce chronic and continuous intestinal blood loss as therapy for congenital polycythemia in a 3 year old child, adult Ancylostoma duodenale were transferred directly from a dog to the patient via a nasoduodenal tube. By transferring adult worms, larval migration via the skin, blood and lungs - with possible attendant undesired side effects - was avoided. Furthermore, by eliminating larval migration with associated intimate tissue contact, immunogenicity was presumably reduced, and a known number of adult worms could be delivered directly to the final predilection site, the small intestine. An eosinophilic reaction of up to 23,000 cells/mm3 was observed, which may have adversely affected attempted superinfection. The relatively small numbers of parasites given on three separate occasions did not result in blood loss to a degree sufficient to eliminate the need for other forms of therapy.

Original languageEnglish (US)
Pages (from-to)217-219
Number of pages3
JournalJournal of Parasitology
Volume70
Issue number2
StatePublished - 1984

Fingerprint

Ancylostoma
Ancylostomatoidea
hookworms
blood
Dogs
therapeutics
dogs
polycythemia
adult children
Superinfection
Polycythemia
skin (animal)
Small Intestine
small intestine
skin
parasite
Parasites
Therapeutics
adverse effects
lungs

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)
  • Microbiology
  • Parasitology

Cite this

Direct transfer of adult hookworms (Ancylostoma duodenale) from dog to child for therapeutic purposes. / Walterspiel, J. N.; Schad, G. A.; Buchanan, G. R.

In: Journal of Parasitology, Vol. 70, No. 2, 1984, p. 217-219.

Research output: Contribution to journalArticle

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