Disordered and dead, but in good company: How a catalytically inactive UTX retains its function

Heankel Cantu Oliveros, Benjamin R. Sabari

Research output: Contribution to journalArticlepeer-review

Abstract

Shi et al. (2021) demonstrate that tumor-suppressive and developmental functions of UTX require an intrinsically disordered region (IDR) capable of condensate formation. These results provide further evidence for the functional role of IDR-mediated spatial organization in regulating gene expression in development and disease.

Original languageEnglish (US)
Pages (from-to)4577-4578
Number of pages2
JournalMolecular cell
Volume81
Issue number22
DOIs
StatePublished - Nov 18 2021

ASJC Scopus subject areas

  • Molecular Biology
  • Cell Biology

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