Distal vessel atherosclerosis as a cause for false-positive renal scintigraphy

Louis Cristol, Brandy Walker, William L. Henrich

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Abstract

While captopril-enhanced renal scintigraphy is acknowledged to be a useful screening technique to detect clinically silent obstructive lesions of the main renal arteries, the presence of significant atherosclerosis of distal, smaller renal vessels as a cause of positive scintigraphy scans has not been reported extensively. In a retrospective 2-year analysis of 31 consecutive captopril-enhanced renal scintigrams, we found a total of 13 studies in 11 patients that were classified as 'positive' for renal artery stenosis. Of these 11 patients with positive scintigraphic studies, 4 patients underwent 5 renal arteriography procedures; only 1 of these renal arteriograms showed significant stenosis of the main renal artery. In the other 4 cases, an angiographic pattern of diffuse intrarenal distal arterial disease correlated with scintigram lateralization. Angiography was also performed in 4 patients with negative captopril renal scintiscans. In each of these cases the arteriogram was also negative for significant renal artery stenosis, and only I patient had diffuse bilateral intrarenal arterial disease. We conclude that distal renal arterial narrowing should be considered in the differential diagnosis of lateralized renal scintigrams. A negative renal scintigraphic study may be more reliable for excluding significant main renal artery obstructive disease.

Original languageEnglish (US)
Pages (from-to)923-930
Number of pages8
JournalRenal Failure
Volume18
Issue number6
StatePublished - 1996

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Radionuclide Imaging
Atherosclerosis
Kidney
Renal Artery Obstruction
Captopril
Renal Artery
Angiography
Differential Diagnosis

ASJC Scopus subject areas

  • Nephrology

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Cristol, L., Walker, B., & Henrich, W. L. (1996). Distal vessel atherosclerosis as a cause for false-positive renal scintigraphy. Renal Failure, 18(6), 923-930.

Distal vessel atherosclerosis as a cause for false-positive renal scintigraphy. / Cristol, Louis; Walker, Brandy; Henrich, William L.

In: Renal Failure, Vol. 18, No. 6, 1996, p. 923-930.

Research output: Contribution to journalArticle

Cristol, L, Walker, B & Henrich, WL 1996, 'Distal vessel atherosclerosis as a cause for false-positive renal scintigraphy', Renal Failure, vol. 18, no. 6, pp. 923-930.
Cristol, Louis ; Walker, Brandy ; Henrich, William L. / Distal vessel atherosclerosis as a cause for false-positive renal scintigraphy. In: Renal Failure. 1996 ; Vol. 18, No. 6. pp. 923-930.
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