Distribution of fibronectin on peripheral blood cells in freshly clotted blood

Frederick Grinnell, Marian K. Feld

Research output: Contribution to journalArticle

19 Scopus citations

Abstract

Blood clots were prepared on plastic substrata and analyzed for fibronectin distribution using indirect immunofluorescence. Platelets generally were observed at focal points where numerous fibrin strands came together and the entire platelet-fibrin meshwork was covered with a uniform coating of fibronectin. In contrast to platelets, other peripheral blood cells observed had no fibronectin on their surfaces, including neutrophils, monocytes, eosinophils, lymphocytes, and red blood cells.

Original languageEnglish (US)
Pages (from-to)397-404
Number of pages8
JournalThrombosis Research
Volume24
Issue number5-6
DOIs
StatePublished - Jan 1 1981

Keywords

  • Fibronectin
  • peripheral blood cells
  • plasma clots
  • platelet-fibrin interactions

ASJC Scopus subject areas

  • Hematology

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