Diuretic Strategies in Acute Decompensated Heart Failure

E. Ashley Hardin, Justin L. Grodin

Research output: Contribution to journalReview article

5 Scopus citations

Abstract

Purpose of Review: The burden of heart failure in the United States is growing rapidly to epic proportions with serious clinical implications for patients and economic strain for healthcare systems. One of the most common reasons for hospitalization in acute decompensated heart failure (ADHF) is excess volume accumulation which leads to untoward symptoms including dyspnea,orthopnea, and edema. Recent Findings: Over the past several decades, there has been great interest in exploring various decongestive strategies in order to achieve symptomatic improvement and favorable clinical outcomes. These include different modalities of loop diuretic administration, the adjunctive use of non-loop diuretics, and other diuretic sparing strategies. Summary: Herein, we provide an appraisal of these decongestive strategies and discuss novel concepts predicting clinical outcomes based on diuretic response and decongestive adequacy while discussing commonly encountered problems such as worsening renal function in ADHF.

Original languageEnglish (US)
Pages (from-to)127-133
Number of pages7
JournalCurrent Heart Failure Reports
Volume14
Issue number2
DOIs
StatePublished - Apr 1 2017

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Keywords

  • Acute decompensated heart failure
  • Decongestive
  • Diuretic
  • Heart failure

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Physiology (medical)
  • Emergency Medicine

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