@article{685c863c81fc4f46bb2737b208866a17,
title = "Diverse classes of T-cell lymphomas arise in T-lymphocyte-inductive epitheliomas of the mouse salivary gland",
abstract = "During the course of serial transplantations of polyomavirus-induced C3H-Bittner salivary gland epitheliomas in F1-hybrid mice, three tumor sublines were found which gave rise to T-cell lymphomas of host origin. The lymphomas resembled spontaneous AKR/J thymic lymphomas in their expression of lymphoid differentiation antigens, and they may represent sequential stages in the differentiation of immature T lymphocytes. We found no evidence that polyomavirus directly induced the lymphomas, rather, the lymphomagenic events paralleled those which occur in spontaneous AKR/J thymic lymphomas.",
keywords = "MuLV, T-cell lymphomas, polyomavirus, salivary gland epitheliomas, thymocytes",
author = "Harrod, {Florence A.} and Kettman, {John R.}",
note = "Funding Information: Acknowledgements--We thank Ms Evangeline Brock for maintaining the in oioo tumor lines; Mr Stuart Pearlman for performing the molecular genetic analyses; and Mses Ann Buser, Lisa Wicktor, and Shehla Ansari for operating the flow cytometers. We are especially grateful to Ms Caroline Humphries for instructing us in the preparation and analysis of genomic DNA and to Dr Miguel Barbosa for reviewing this manuscript. We gratefully acknowledge Mr and Mrs Sylvio Pefia for operating the mouse breeding colony and producing the F1 hybrids used in this research. These studies were supported by Cancer Immunology Training Grant 5T32-CA09082 from the National Cancer Institute and DHHS Research Grants AIl1851 and CA41679.",
year = "1992",
month = sep,
doi = "10.1016/0145-2126(92)90036-7",
language = "English (US)",
volume = "16",
pages = "899--917",
journal = "Leukemia Research",
issn = "0145-2126",
publisher = "Elsevier Limited",
number = "9",
}