DNA diagnosis confirms hemoglobin deletion in newborn screen follow-up

Urvashi Bhardwaj, Yao Hua Zhang, Desirée S. Jackson, George R. Buchanan, Bradford L. Therrell, Linda L. McCabe, Edward R B McCabe

Research output: Contribution to journalArticle

8 Scopus citations

Abstract

Molecular genetic confirmatory testing with polymerase chain reaction amplification is integral to neonatal hemoglobinopathy screening programs. In this study, we demonstrate applicability of polymerase chain reaction-based testing for the common deletions in blacks responsible for hereditary persistence of fetal hemoglobin. This approach will provide rapid diagnostic clarification in newborn screening follow-up.

Original languageEnglish (US)
Pages (from-to)346-348
Number of pages3
JournalJournal of Pediatrics
Volume142
Issue number3
DOIs
Publication statusPublished - Mar 1 2003

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ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Bhardwaj, U., Zhang, Y. H., Jackson, D. S., Buchanan, G. R., Therrell, B. L., McCabe, L. L., & McCabe, E. R. B. (2003). DNA diagnosis confirms hemoglobin deletion in newborn screen follow-up. Journal of Pediatrics, 142(3), 346-348. https://doi.org/10.1067/mpd.2003.117