DNA diagnosis confirms hemoglobin deletion in newborn screen follow-up

Urvashi Bhardwaj, Yao Hua Zhang, Desirée S. Jackson, George R. Buchanan, Bradford L. Therrell, Linda L. McCabe, Edward R B McCabe

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Molecular genetic confirmatory testing with polymerase chain reaction amplification is integral to neonatal hemoglobinopathy screening programs. In this study, we demonstrate applicability of polymerase chain reaction-based testing for the common deletions in blacks responsible for hereditary persistence of fetal hemoglobin. This approach will provide rapid diagnostic clarification in newborn screening follow-up.

Original languageEnglish (US)
Pages (from-to)346-348
Number of pages3
JournalJournal of Pediatrics
Volume142
Issue number3
DOIs
StatePublished - Mar 1 2003

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Hemoglobins
Newborn Infant
Neonatal Screening
Fetal Hemoglobin
Hemoglobinopathies
Polymerase Chain Reaction
DNA
Genetic Testing
Molecular Biology

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Bhardwaj, U., Zhang, Y. H., Jackson, D. S., Buchanan, G. R., Therrell, B. L., McCabe, L. L., & McCabe, E. R. B. (2003). DNA diagnosis confirms hemoglobin deletion in newborn screen follow-up. Journal of Pediatrics, 142(3), 346-348. https://doi.org/10.1067/mpd.2003.117

DNA diagnosis confirms hemoglobin deletion in newborn screen follow-up. / Bhardwaj, Urvashi; Zhang, Yao Hua; Jackson, Desirée S.; Buchanan, George R.; Therrell, Bradford L.; McCabe, Linda L.; McCabe, Edward R B.

In: Journal of Pediatrics, Vol. 142, No. 3, 01.03.2003, p. 346-348.

Research output: Contribution to journalArticle

Bhardwaj, U, Zhang, YH, Jackson, DS, Buchanan, GR, Therrell, BL, McCabe, LL & McCabe, ERB 2003, 'DNA diagnosis confirms hemoglobin deletion in newborn screen follow-up', Journal of Pediatrics, vol. 142, no. 3, pp. 346-348. https://doi.org/10.1067/mpd.2003.117
Bhardwaj U, Zhang YH, Jackson DS, Buchanan GR, Therrell BL, McCabe LL et al. DNA diagnosis confirms hemoglobin deletion in newborn screen follow-up. Journal of Pediatrics. 2003 Mar 1;142(3):346-348. https://doi.org/10.1067/mpd.2003.117
Bhardwaj, Urvashi ; Zhang, Yao Hua ; Jackson, Desirée S. ; Buchanan, George R. ; Therrell, Bradford L. ; McCabe, Linda L. ; McCabe, Edward R B. / DNA diagnosis confirms hemoglobin deletion in newborn screen follow-up. In: Journal of Pediatrics. 2003 ; Vol. 142, No. 3. pp. 346-348.
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