Do nonclassical, class Ib MHC molecules present bacterial antigens to T cells?

Eric G. Pamer, Michael J. Bevan, Kirsten Fischer Lindahl

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

Immune responses to bacterial antigens that appear unrestricted by the MHC may involve oligomorphic MHC class Ib H-2M3, which binds N-formylated peptides and presents a Listeria peptide to cytotoxic T cells from infected mice. Lack of polymorphism makes these molecules a promising target for peptide vaccines.

Original languageEnglish (US)
Pages (from-to)35-38
Number of pages4
JournalTrends in Microbiology
Volume1
Issue number1
DOIs
StatePublished - 1993

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Bacterial Antigens
N-Formylmethionine Leucyl-Phenylalanine
Listeria
Subunit Vaccines
T-Lymphocytes
Peptides

ASJC Scopus subject areas

  • Microbiology
  • Infectious Diseases

Cite this

Do nonclassical, class Ib MHC molecules present bacterial antigens to T cells? / Pamer, Eric G.; Bevan, Michael J.; Lindahl, Kirsten Fischer.

In: Trends in Microbiology, Vol. 1, No. 1, 1993, p. 35-38.

Research output: Contribution to journalArticle

Pamer, Eric G. ; Bevan, Michael J. ; Lindahl, Kirsten Fischer. / Do nonclassical, class Ib MHC molecules present bacterial antigens to T cells?. In: Trends in Microbiology. 1993 ; Vol. 1, No. 1. pp. 35-38.
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