Do nonclassical, class Ib MHC molecules present bacterial antigens to T cells?

Eric G. Pamer, Michael J. Bevan, Kirsten Fischer Lindahl

Research output: Contribution to journalComment/debatepeer-review

21 Scopus citations

Abstract

Immune responses to bacterial antigens that appear unrestricted by the MHC may involve oligomorphic MHC class Ib H-2M3, which binds N-formylated peptides and presents a Listeria peptide to cytotoxic T cells from infected mice. Lack of polymorphism makes these molecules a promising target for peptide vaccines.

Original languageEnglish (US)
Pages (from-to)35-38
Number of pages4
JournalTrends in Microbiology
Volume1
Issue number1
DOIs
StatePublished - Apr 1993

ASJC Scopus subject areas

  • Microbiology
  • Microbiology (medical)
  • Infectious Diseases
  • Virology

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