Dobutamine echocardiography in predicting improvement in global left ventricular systolic function after coronary bypass or angioplasty in patients with healed myocardial infarcts

Jaroslav Meluzin, Carlos G. Cigarroa, M. Elizabeth Brickner, Jan Cerny, Lenka Spinarova, Milan Frelich, Frantisek Stetka, Ladislav Groch, Paul A. Grayburn

Research output: Contribution to journalArticle

59 Scopus citations

Abstract

The aim of this study was to determine whether low-dose dobutamine ecnocardiography (DE) could predict quantitative improvement in global left ventricular (LV) systolic function after coronary revascularization. Low-dose DE was performed in 71 consecutive patients with coronary artery disease and LV dysfunction. Successful coronary bypass surgery or angioplasty was performed in 44 patients, 37 of whom had a resting echocardiogram 1 to 3 months afterward. Group A consisted of 20 patients with contractile reserve during DE, and group B consisted of 17 patients without contractile reserve. As expected, regional wall motion score index (mean ± SD) improved in group A (1.62 ± 0.39 to 1.38 ± 0.31, p < 0.01) but not group B (1.56 ± 0.42 to 1.57 ± 0.41, p = NS). In addition, LV ejection fraction (LVEF) improved after bypass surgery or angio plasty in group A (38 ± 5% to 42 ± 5%, p < 0.01), but not in group B (38 ± 7% to 39 ± 8%, p = NS). In group A, a significant linear correlation was observed between the number of segments with contractile reserve and the improvement in LVEF (r = 0.91, p < 0.0001). A good correlation also existed between the improvement in regional wall motion score index during dobutamine infusion and the improvement in LVEF after bypass surgery or angioplasty (r = 0.90, p < 0.0001). In conclusion, low-dose DE can be used to predict quantitative improvement in global LV systolic function after coronary bypass or angioplasty.

Original languageEnglish (US)
Pages (from-to)877-880
Number of pages4
JournalThe American journal of cardiology
Volume76
Issue number12
DOIs
StatePublished - Nov 1 1995

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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