Dopaminergic rules of engagement for memory in Drosophila

Karla R. Kaun, Adrian Rothenfluh

Research output: Contribution to journalReview article

14 Scopus citations

Abstract

Dopamine is associated with a variety of conserved responses across species including locomotion, sleep, food consumption, aggression, courtship, addiction and several forms of appetitive and aversive memory. Historically, dopamine has been most prominently associated with dynamics underlying reward, punishment, or salience. Recent emerging evidence from Drosophila supports a role in all of these functions, as well as additional roles in the interplay between external sensation and internal states and forgetting of the very memories dopamine helped encode. We discuss how cell-specific resolution and manipulation are elucidating the rules of dopamine's involvement in encoding valence and memory.

Original languageEnglish (US)
Pages (from-to)56-62
Number of pages7
JournalCurrent Opinion in Neurobiology
Volume43
DOIs
StatePublished - Apr 1 2017

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ASJC Scopus subject areas

  • Neuroscience(all)

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