Drug-Coated Balloon and Stent Therapies for Endovascular Treatment of Atherosclerotic Superficial Femoral Artery Disease

Subhash Banerjee, Karan Sarode, Atif Mohammad, Emmanouil S. Brilakis

Research output: Contribution to journalArticle

4 Scopus citations

Abstract

Endovascular management of superficial femoral artery disease has historically been limited to percutaneous balloon angioplasty, atherectomy, and bare-metal stents. However, these therapies have been plagued by high restenosis and target lesion revascularization rates. More recent technologies such as drug-coated stents and balloons are designed to combat restenosis by locally delivering antiproliferative drugs. Several randomized controlled trials have directly compared these antiproliferative drug-delivering devices to their non-drug-coated counterparts. Additionally, trials are currently ongoing to compare use of drug-coated technologies in combination with traditional therapies in hope of synergistic effects. This review gathers data from currently published clinical trials, provides an overview of upcoming clinical studies utilizing drug-coated technology, and explores the possible impact these devices may have on clinical practice.

Original languageEnglish (US)
JournalCurrent Cardiology Reports
Volume17
Issue number5
DOIs
StatePublished - May 1 2015

Keywords

  • Chronic total occlusion
  • Drug-coated balloons
  • Drug-coated stents
  • Endovascular revascularization
  • Peripheral artery disease
  • Superficial femoral artery

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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