Drug-eluting stents in saphenous vein graft interventions: A systematic review

Research output: Contribution to journalReview article

39 Scopus citations

Abstract

Aims: A systematic review of the outcomes after drug-eluting stents (DES) implantation in saphenous vein grafts (SVGs) was performed. Methods and results: The majority of the 33 published studies were retrospective with only two prospective randomised trials. Late loss and binary restenosis was reduced compared to bare metal stents (BMS) in all seven studies with angiographic follow-up. With the exception of one study there was no difference in mortality, myocardial infarction, or stent thrombosis between BMS and DES. The need for repeat target vessel or lesion revascularisation was lower in the DES arm in approximately half the published studies and similar in the remaining studies. Conclusions: Until data from large, prospective, randomised-controlled studies become available, DES implantation in SVGs appears to be safe and, although not yet definitively proven, likely to reduce angiographic restenosis and the need for repeat target lesion revascularisation.

Original languageEnglish (US)
Pages (from-to)722-730
Number of pages9
JournalEuroIntervention
Volume5
Issue number6
DOIs
StatePublished - Jan 1 2010

Keywords

  • Drug-eluting stents
  • Percutaneous coronary intervention
  • Saphenous vein grafts

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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