Drug-Induced Liver Injury

B. S. Apica; W. M. Lee

doi:10.1016/B978-0-12-386456-7.04208-8

Drug-Induced Liver Injury

B. S. Apica, W. M. Lee

Research output: Chapter in Book/Report/Conference proceeding › Chapter

3 Scopus citations

Abstract

Drug-induced Liver injury is a common cause of Liver necrosis of exceptional severity, comprising more than 50% of all cases of acute Liver failure in the United States. Hepatotoxicity has been described for a large number of drugs, although the overall number of cases of each is quite low, given the number of prescriptions written.

Original language	English (US)
Title of host publication	Pathobiology of Human Disease
Subtitle of host publication	A Dynamic Encyclopedia of Disease Mechanisms
Publisher	Elsevier Inc.
Pages	1825-1837
Number of pages	13
ISBN (Electronic)	9780123864567
ISBN (Print)	9780123864574
DOIs	https://doi.org/10.1016/B978-0-12-386456-7.04208-8
State	Published - Jan 1 2014
Externally published	Yes

Keywords

Apoptosis
CausaLity
Cholestatic
Hepatocellular
Hepatotoxicity
Immunoallergic
Necrosis

ASJC Scopus subject areas

General Medicine

Access to Document

10.1016/B978-0-12-386456-7.04208-8

Cite this

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title = "Drug-Induced Liver Injury",

abstract = "Drug-induced Liver injury is a common cause of Liver necrosis of exceptional severity, comprising more than 50% of all cases of acute Liver failure in the United States. Hepatotoxicity has been described for a large number of drugs, although the overall number of cases of each is quite low, given the number of prescriptions written.",

keywords = "Apoptosis, CausaLity, Cholestatic, Hepatocellular, Hepatotoxicity, Immunoallergic, Necrosis",

author = "Apica, {B. S.} and Lee, {W. M.}",

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AU - Lee, W. M.

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AB - Drug-induced Liver injury is a common cause of Liver necrosis of exceptional severity, comprising more than 50% of all cases of acute Liver failure in the United States. Hepatotoxicity has been described for a large number of drugs, although the overall number of cases of each is quite low, given the number of prescriptions written.

KW - Apoptosis

KW - CausaLity

KW - Cholestatic

KW - Hepatocellular

KW - Hepatotoxicity

KW - Immunoallergic

KW - Necrosis

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BT - Pathobiology of Human Disease

PB - Elsevier Inc.

ER -

Drug-Induced Liver Injury

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

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