Drug-Induced Liver Injury

B. S. Apica, William M Lee

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Abstract

Drug-induced Liver injury is a common cause of Liver necrosis of exceptional severity, comprising more than 50% of all cases of acute Liver failure in the United States. Hepatotoxicity has been described for a large number of drugs, although the overall number of cases of each is quite low, given the number of prescriptions written.

Original languageEnglish (US)
Title of host publicationPathobiology of Human Disease
Subtitle of host publicationA Dynamic Encyclopedia of Disease Mechanisms
PublisherElsevier Inc.
Pages1825-1837
Number of pages13
ISBN (Electronic)9780123864567
ISBN (Print)9780123864574
DOIs
StatePublished - Jan 1 2014
Externally publishedYes

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Keywords

  • Apoptosis
  • CausaLity
  • Cholestatic
  • Hepatocellular
  • Hepatotoxicity
  • Immunoallergic
  • Necrosis

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Apica, B. S., & Lee, W. M. (2014). Drug-Induced Liver Injury. In Pathobiology of Human Disease: A Dynamic Encyclopedia of Disease Mechanisms (pp. 1825-1837). Elsevier Inc.. https://doi.org/10.1016/B978-0-12-386456-7.04208-8