Dutasteride significantly improves quality of life measures in patients with enlarged prostate

M. P. O'Leary, Claus Roehrborn, L. Black

Research output: Contribution to journalArticle

12 Scopus citations

Abstract

The purpose of this study was to determine the effect of dutasteride on quality of life of men with lower urinary tract symptoms associated with enlarged prostate or benign prostatic hyperplasia (BPH) as measured by symptom problem index (SPI), BPH-specific interference with activities (BSIA), BPH-specific psychological well-being (BPWB) and BPH-specific lifestyle adaptations (BSLA). Data were derived from three randomized, double-blind studies conducted in 4325 men treated with placebo or dutasteride (0.5 mg/day). Primary analyses included changes from baseline in mean SPI, BSIA, BPWB and BSLA scores. Men treated with dutasteride showed significant improvements in SPI, BSIA, BPWB and BSLA scores compared with placebo.

Original languageEnglish (US)
Pages (from-to)129-133
Number of pages5
JournalProstate Cancer and Prostatic Diseases
Volume11
Issue number2
DOIs
StatePublished - Jun 1 2008

ASJC Scopus subject areas

  • Oncology
  • Urology
  • Cancer Research

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