TY - JOUR
T1 - Dutasteride significantly improves quality of life measures in patients with enlarged prostate
AU - O'Leary, M. P.
AU - Roehrborn, Claus
AU - Black, L.
PY - 2008/6
Y1 - 2008/6
N2 - The purpose of this study was to determine the effect of dutasteride on quality of life of men with lower urinary tract symptoms associated with enlarged prostate or benign prostatic hyperplasia (BPH) as measured by symptom problem index (SPI), BPH-specific interference with activities (BSIA), BPH-specific psychological well-being (BPWB) and BPH-specific lifestyle adaptations (BSLA). Data were derived from three randomized, double-blind studies conducted in 4325 men treated with placebo or dutasteride (0.5 mg/day). Primary analyses included changes from baseline in mean SPI, BSIA, BPWB and BSLA scores. Men treated with dutasteride showed significant improvements in SPI, BSIA, BPWB and BSLA scores compared with placebo.
AB - The purpose of this study was to determine the effect of dutasteride on quality of life of men with lower urinary tract symptoms associated with enlarged prostate or benign prostatic hyperplasia (BPH) as measured by symptom problem index (SPI), BPH-specific interference with activities (BSIA), BPH-specific psychological well-being (BPWB) and BPH-specific lifestyle adaptations (BSLA). Data were derived from three randomized, double-blind studies conducted in 4325 men treated with placebo or dutasteride (0.5 mg/day). Primary analyses included changes from baseline in mean SPI, BSIA, BPWB and BSLA scores. Men treated with dutasteride showed significant improvements in SPI, BSIA, BPWB and BSLA scores compared with placebo.
UR - http://www.scopus.com/inward/record.url?scp=43549124856&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=43549124856&partnerID=8YFLogxK
U2 - 10.1038/sj.pcan.4500990
DO - 10.1038/sj.pcan.4500990
M3 - Article
C2 - 17592479
AN - SCOPUS:43549124856
SN - 1365-7852
VL - 11
SP - 129
EP - 133
JO - Prostate Cancer and Prostatic Diseases
JF - Prostate Cancer and Prostatic Diseases
IS - 2
ER -