Economy in the use of muscle relaxants Vecuronium after pancuronium

B. Kay, R. J. Chestnut, J. S T Sum Ping, T. E J Healy

Research output: Contribution to journalArticle

9 Scopus citations

Abstract

Vecuronium is an intermediate duration, non‐depolarising muscle relaxant. When used during prolonged procedures, it may be given by intermittent injection, by continuous infusion or by a single very large dose at the start of anaesthesia. It may also be used to maintain relaxation after the initial use of a long‐acting agent, such as pancuronium. This study demonstrates that the effect of a dose of vecuronium used in this fashion is increased when interaction with pancuronium takes place. The clinical and theoretical implications of this observation are discussed.

Original languageEnglish (US)
Pages (from-to)277-280
Number of pages4
JournalAnaesthesia
Volume42
Issue number3
DOIs
StatePublished - Mar 1987

Keywords

  • Neuromuscular relaxants; pancuronium, vecuronium

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine

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