EEG alpha photic driving abnormalities in chronic schizophrenia

Daniel M. Rice, Steven G. Potkin, Yi Jin, Robert Isenhart, C. W.Chris Heh, John Sramek, Jerome Costa, Curt A. Sandman

Research output: Contribution to journalArticlepeer-review

Abstract

Periodic photic stimuli across the entire electroencephalographic (EEG) frequency range were used in an attempt to assess EEG functional differences between chronic schizophrenic patients and control subjects. The EEG responses to these photic stimuli were significantly attenuated in the schizophrenic patients, specifically at the frequencies within the EEG alpha range. The schizophrenic patients also showed an alpha range attenuation in the "no stimulus" EEG alpha measure, such that there was a significant correlation across subjects between the "stimulus" and "no stimulus" EEG alpha range abnormalities. These abnormalities are discussed with reference to possible dysfunctional thalamic mechanisms involved in the pacing of EEG alpha activity and the gating of information through the cerebral cortex.

Original languageEnglish (US)
Pages (from-to)313-324
Number of pages12
JournalPsychiatry research
Volume30
Issue number3
DOIs
StatePublished - Dec 1989
Externally publishedYes

Keywords

  • EEG photic driving
  • Electroencephalographic (EEG) alpha rhythm
  • schizophrenia
  • thalamus

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Biological Psychiatry

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