Effect of a novel 5-HT₃ receptor antagonist carboxamide, 3-methoxy-N-p-tolylquinoxalin-2-carboxamide (QCM-4) on the acute and chronic rodent models of depression

Medicine & Life Sciences

• 3-methoxy-N-p-tolylquinoxalin-2-carboxamide 100%
• Serotonin 5-HT3 Receptor Antagonists 57%
• Receptors, Serotonin, 5-HT3 55%
• Hindlimb Suspension 55%
• Anatomic Models 55%
• Induced Hypothermia 52%
• Reserpine 50%
• Sucrose 41%
• Serotonin 36%
• Rodentia 34%
• Head 30%
• Anhedonia 27%
• Depression 27%
• Animals 21%
• Ion Channels 20%
• Antidepressive Agents 18%
• Walking 18%
• Cognition 16%
• Anxiety 15%
• Therapeutics 3%

Chemical Compounds

• Serotonin 5-HT3 Receptor Antagonist 67%
• Antidepressant 53%
• Carboxamide 48%
• Reserpine 39%
• Sucrose 26%
• Suspension 21%
• Dose 21%
• Reduction 6%
• Ion 5%