Abstract
Chemical deglycosylation of ricin A-chain virtually eliminated its entrapment by the liver and delayed its clearance from the bloodstream of mice. Liver entrapment of native ricin A-chain occured to approximately equal extents in the parenchymal and non-parenchymal cell fractions of the liver. The chemical deglycosylation procedure reduced uptake of the A-chain by both cell fractions.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 189-196 |
| Number of pages | 8 |
| Journal | Cancer Drug Delivery |
| Volume | 3 |
| Issue number | 3 |
| DOIs | |
| State | Published - 1986 |
ASJC Scopus subject areas
- Pharmacology
- Cancer Research