Effect of Donor Nephrectomy Technique on Recipient Lymphatic Drainage

Tzevat Tefik, H. S. Ciftci, T. Kocak, O. Sanli, H. Ander, O. Ziylan, T. Oktar, S. Verep, Y. Caliskan, A. Turkmen, F. S. Oguz, I. Nane

Research output: Contribution to journalArticle

Abstract

Aim We sought to evaluate the postoperative recipient lymphatic drainage depending on open donor nephrectomy (ODN) or laparoscopic (LDN) techniques. Method Between March 2012 and August 2014, 58 patients underwent renal transplantation from living-related donors. Thirty donors underwent ODN (group 1), and 28 LDN (group 2). Operations were performed by the same surgeons. Both cranial and caudal drainage catheters for lymphatic leakage were placed preoperatively and all the recipients received tacrolimus, mycophenolate mofetil, and steroid as immunosuppressive regimen. None of the patients had coagulation abnormalities. Results All grafts were functioning during the early postoperative period and diuresis was ensured. No difference was observed on early postoperative period regarding to acute rejection (P =.329) or infection (P =.546). No difference was seen concerning mycophenolate mofetil and mycophenolate sodium regimens among the 2 groups (P =.227). In groups 1 and 2, the cranial drainage catheters were not taken out until postoperative days 5.5 ± 2.5 (range, 0-11) and 6.4 ± 3.8 (range, 0-14) and the caudal catheters stayed in place until days 8.8 ± 3.5 (range, 1-16) and 9.9 ± 5.9 (range, 3-22), respectively. No difference was found when comparing the cranial (P =.308) and caudal (P =.426) drainage periods. However, during clinical acute rejection episodes the cranial drainage period was longer in group 1 (P =.003). Three patients developed lymphoceles, 1 requiring drainage, in group 2. Conclusions There seems to be no difference in recipient lymphatic drainage by donor nephrectomy technique. A laparoscopic procedure may be advantageous owing to shorter lymphatic drainage during clinical acute rejection episodes.

Original languageEnglish (US)
Pages (from-to)1282-1286
Number of pages5
JournalTransplantation Proceedings
Volume47
Issue number5
DOIs
StatePublished - Jun 1 2015

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Nephrectomy
Drainage
Tissue Donors
Mycophenolic Acid
Catheters
Postoperative Period
Lymphocele
Living Donors
Diuresis
Tacrolimus
Immunosuppressive Agents
Kidney Transplantation
Steroids
Transplants
Infection

ASJC Scopus subject areas

  • Surgery
  • Transplantation
  • Medicine(all)

Cite this

Effect of Donor Nephrectomy Technique on Recipient Lymphatic Drainage. / Tefik, Tzevat; Ciftci, H. S.; Kocak, T.; Sanli, O.; Ander, H.; Ziylan, O.; Oktar, T.; Verep, S.; Caliskan, Y.; Turkmen, A.; Oguz, F. S.; Nane, I.

In: Transplantation Proceedings, Vol. 47, No. 5, 01.06.2015, p. 1282-1286.

Research output: Contribution to journalArticle

Tefik, T, Ciftci, HS, Kocak, T, Sanli, O, Ander, H, Ziylan, O, Oktar, T, Verep, S, Caliskan, Y, Turkmen, A, Oguz, FS & Nane, I 2015, 'Effect of Donor Nephrectomy Technique on Recipient Lymphatic Drainage', Transplantation Proceedings, vol. 47, no. 5, pp. 1282-1286. https://doi.org/10.1016/j.transproceed.2015.04.079
Tefik, Tzevat ; Ciftci, H. S. ; Kocak, T. ; Sanli, O. ; Ander, H. ; Ziylan, O. ; Oktar, T. ; Verep, S. ; Caliskan, Y. ; Turkmen, A. ; Oguz, F. S. ; Nane, I. / Effect of Donor Nephrectomy Technique on Recipient Lymphatic Drainage. In: Transplantation Proceedings. 2015 ; Vol. 47, No. 5. pp. 1282-1286.
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AU - Tefik, Tzevat

AU - Ciftci, H. S.

AU - Kocak, T.

AU - Sanli, O.

AU - Ander, H.

AU - Ziylan, O.

AU - Oktar, T.

AU - Verep, S.

AU - Caliskan, Y.

AU - Turkmen, A.

AU - Oguz, F. S.

AU - Nane, I.

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N2 - Aim We sought to evaluate the postoperative recipient lymphatic drainage depending on open donor nephrectomy (ODN) or laparoscopic (LDN) techniques. Method Between March 2012 and August 2014, 58 patients underwent renal transplantation from living-related donors. Thirty donors underwent ODN (group 1), and 28 LDN (group 2). Operations were performed by the same surgeons. Both cranial and caudal drainage catheters for lymphatic leakage were placed preoperatively and all the recipients received tacrolimus, mycophenolate mofetil, and steroid as immunosuppressive regimen. None of the patients had coagulation abnormalities. Results All grafts were functioning during the early postoperative period and diuresis was ensured. No difference was observed on early postoperative period regarding to acute rejection (P =.329) or infection (P =.546). No difference was seen concerning mycophenolate mofetil and mycophenolate sodium regimens among the 2 groups (P =.227). In groups 1 and 2, the cranial drainage catheters were not taken out until postoperative days 5.5 ± 2.5 (range, 0-11) and 6.4 ± 3.8 (range, 0-14) and the caudal catheters stayed in place until days 8.8 ± 3.5 (range, 1-16) and 9.9 ± 5.9 (range, 3-22), respectively. No difference was found when comparing the cranial (P =.308) and caudal (P =.426) drainage periods. However, during clinical acute rejection episodes the cranial drainage period was longer in group 1 (P =.003). Three patients developed lymphoceles, 1 requiring drainage, in group 2. Conclusions There seems to be no difference in recipient lymphatic drainage by donor nephrectomy technique. A laparoscopic procedure may be advantageous owing to shorter lymphatic drainage during clinical acute rejection episodes.

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