Effect of indomethacin on changes of acute ureteral pressure elevation in the dog

G. A. Edwards, W. N. Suki

Research output: Contribution to journalArticle

Abstract

The effects of indomethacin on hemodynamic and excretory alterations produced by acute ureteral obstruction were investigated in anesthetized dogs by means of radiolabeled microspheres and clearance techniques. Renal blood flow in untreated animals increased by 40 ± 12% with acute ureteral pressure elevation in comparison to the contralateral unobstructed kidney. This increase was only 7±3% (p

Original languageEnglish (US)
Pages (from-to)154-165
Number of pages12
JournalKidney and Blood Pressure Research
Volume1
Issue number3
DOIs
StatePublished - 1978

Keywords

  • Dog
  • Indomethacin
  • Obstruction acute
  • Ureteral pressure

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Nephrology

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