Effect of iodine supplementation on goiter prevalence among the pediatric population in a severely iodine deficient area

Fatma Demirel, Tülay Özer, Ahmet Gürel, Ceyda Acun, Hüseyin Özdemir, Nazan Tomaç, Murat Ünalacak

Research output: Contribution to journalArticle

9 Scopus citations


We evaluated goiter status and urinary iodine excretion (UIC) of 304 school-children (7-12 years old) 3 years after a law was passed for mandatory production of iodinated salt in an area previously characterized by severe iodine deficiency in Zonguldak, a mountainous city in the West Black Sea region in Turkey. We examined all the children for goiter by palpation, measured sonographic thyroid volumes (STV) and UIC. Eighty-two percent of families had been using iodinated salt. UIC was above 100 μg/l in 71.2% of the children and median UIC was sufficient (143.5 μg/l). The prevalence of goiter was lower at ultrasound (14.6%) than by palpation (19.4%). Median STV values were within recommended normal limits at all ages. Although Zonguldak had been a highly endemic region, it became mildly endemic 3 years after mandatory iodination of salt, with decrease of goiter prevalence.

Original languageEnglish (US)
Pages (from-to)73-76
Number of pages4
JournalJournal of Pediatric Endocrinology and Metabolism
Issue number1
StatePublished - Jan 1 2004



  • Endemic goiter
  • Iodinated salt
  • Iodine deficiency
  • Thyroid volume
  • Turkey

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Endocrinology, Diabetes and Metabolism
  • Endocrinology

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