Effect of parathyroidectomy on serum 1α,25-dihydroxyvitamin D and intestinal calcium absorption in primary hyperparathyroidism

H. G. Bone, J. E. Zerwekh, M. R. Haussler, C. Y C Pak

Research output: Contribution to journalArticle

32 Citations (Scopus)

Abstract

Serum concentration of 1α,25-dihydroxyvitamin D [1,25(OH)2D] and intestinal absorption were measured before and after parathyroidectomy in 11 patients with primary hyperparathyroidism. Serum 1,25(OH)2D was high preoperatively (P < 0.001) and normal postoperatively. Ca absorption was elevated preoperatively (P < 0.001) and decreased significantly after parathyroidectomy (P < 0.001). However, 5 of 11 patients had a persistent hyperabsorption of Ca postoperatively, despite normal serum 1,25(OH)2D. The results suggest that factors other than 1,25(OH)2D contribute to the maintenance of high intestinal Ca absorption in hyperparathyroid patients in the postoperative state.

Original languageEnglish (US)
Pages (from-to)877-879
Number of pages3
JournalJournal of Clinical Endocrinology and Metabolism
Volume48
Issue number5
StatePublished - 1979

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Parathyroidectomy
Primary Hyperparathyroidism
Intestinal Absorption
Calcium
Serum
1,25-dihydroxyvitamin D

ASJC Scopus subject areas

  • Biochemistry
  • Endocrinology, Diabetes and Metabolism

Cite this

Effect of parathyroidectomy on serum 1α,25-dihydroxyvitamin D and intestinal calcium absorption in primary hyperparathyroidism. / Bone, H. G.; Zerwekh, J. E.; Haussler, M. R.; Pak, C. Y C.

In: Journal of Clinical Endocrinology and Metabolism, Vol. 48, No. 5, 1979, p. 877-879.

Research output: Contribution to journalArticle

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