Effect of proximity to hazardous waste sites on the development of congenital heart disease

Sadia Malik, Arnold Schecter, Margaret Caughy, David E Fixler

Research output: Contribution to journalArticlepeer-review

22 Scopus citations


The authors sought to determine whether the risk of congenital heart disease (CHD) was greater for the children of mothers who lived close to a hazardous waste site (HWS) than for those who lived farther away. All cases (n = 1283) of confirmed CHD, and a random sample of 2,292 controls, born in Dallas County, Texas, from 1979-1984 were linked with 276 HWSs present during the study. The authors ascertained locations of households and determined the distance to the nearest HWS. They obtained odds ratios (ORs) for CHD. A 20% increased risk for CHD was found in association with maternal residence within 1 mile of an HWS (OR = 1.2, 95% confidence interval = 1.1-1.4). The results of this study suggests that a statistically significant additional risk for CHD is associated with maternal proximity to an HWS.

Original languageEnglish (US)
Pages (from-to)177-181
Number of pages5
JournalArchives of Environmental Health
Issue number4
StatePublished - Apr 2004


  • Birth defects
  • Congenital heart disease
  • Hazardous waste

ASJC Scopus subject areas

  • Environmental Chemistry
  • Environmental Science(all)
  • Public Health, Environmental and Occupational Health
  • Health, Toxicology and Mutagenesis


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