Effect of simvastatin versus placebo on treadmill exercise time until the onset of intermittent claudication in older patients with peripheral arterial disease at six months and at one year after treatment

Wilbert S. Aronow, Devraj Nayak, Steven Woodworth, Chul Ahn

Research output: Contribution to journalArticle

163 Scopus citations

Abstract

Simvastatin significantly increased treadmill exercise time until onset of intermittent claudication from baseline by 54 seconds (a 24% increase, p <0.0001) at 6 months after treatment and by 95 seconds (a 42% increase, p <0.0001) at 1 year after treatment. At 6 months and 1 year after treatment with placebo, treadmill exercise time until onset of intermittent claudication was not significantly different from baseline exercise time.

Original languageEnglish (US)
Pages (from-to)711-712
Number of pages2
JournalAmerican Journal of Cardiology
Volume92
Issue number6
DOIs
StatePublished - Sep 15 2003

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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