Effect of skin-graft harvesting on hair growth: Implications for the study of alopecia

L. Li, J. B. Robinson, R. J. Rohrich

Research output: Contribution to journalArticlepeer-review

Abstract

An experiment using guinea pigs was performed to demonstrate the feasibility of repeated skin-graft harvesting as a model system in the study of diffuse alopecia. In response to four split-thickness skin harvests from the same site at 2-week intervals, the number of hairs observed and follicular area doubled, implying a transition of hair follicles from vellus to terminal, compared with ungrafted control skin from the alternate side of the same animals. The guinea pig may serve as a future model for the study of diffuse alopecia because its hair growth patterns are similar to those observed in humans.

Original languageEnglish (US)
Pages (from-to)539-541
Number of pages3
JournalAnnals of plastic surgery
Volume34
Issue number5
DOIs
StatePublished - May 30 1995

ASJC Scopus subject areas

  • Surgery

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