Effect of sodium cellulose phosphate therapy on crystallization of calcium oxalate in urine

Yasufumi Hayashi, Roy A. Kaplan, Charles Y C Pak

Research output: Contribution to journalArticle

28 Scopus citations

Abstract

Effects of oral sodium cellulose phosphate therapy (5 g three times a day with meals for 4 days) on renal excretion of oxalate and on the crystallization of calcium oxalate in urine were examined in six patients with absorptive hypercalciuria on a constant metabolic dietary regimen. During treatment, urinary oxalate increased by 9-50 mg/day. However, urinary calcium decreased by 138-225 mg/day (50%-70%). Thus, the state of saturation of urine with respect to calcium oxalate decreased or did not change significantly. There was no consistent or significant change in the formation product ratio (limit of metastability) or in the crystal growth of calcium oxalate in urine.

Original languageEnglish (US)
Pages (from-to)1273-1278
Number of pages6
JournalMetabolism
Volume24
Issue number11
DOIs
StatePublished - Nov 1975

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Endocrinology

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