Effect of sodium cellulose phosphate therapy on crystallization of calcium oxalate in urine

Yasufumi Hayashi; Roy A. Kaplan; Charles Y C Pak

doi:10.1016/0026-0495(75)90065-7

Effect of sodium cellulose phosphate therapy on crystallization of calcium oxalate in urine

Yasufumi Hayashi, Roy A. Kaplan, Charles Y C Pak

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Abstract

Effects of oral sodium cellulose phosphate therapy (5 g three times a day with meals for 4 days) on renal excretion of oxalate and on the crystallization of calcium oxalate in urine were examined in six patients with absorptive hypercalciuria on a constant metabolic dietary regimen. During treatment, urinary oxalate increased by 9-50 mg/day. However, urinary calcium decreased by 138-225 mg/day (50%-70%). Thus, the state of saturation of urine with respect to calcium oxalate decreased or did not change significantly. There was no consistent or significant change in the formation product ratio (limit of metastability) or in the crystal growth of calcium oxalate in urine.

Original language	English (US)
Pages (from-to)	1273-1278
Number of pages	6
Journal	Metabolism
Volume	24
Issue number	11
DOIs	https://doi.org/10.1016/0026-0495(75)90065-7
State	Published - Nov 1975

ASJC Scopus subject areas

Endocrinology, Diabetes and Metabolism
Endocrinology

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10.1016/0026-0495(75)90065-7

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title = "Effect of sodium cellulose phosphate therapy on crystallization of calcium oxalate in urine",

abstract = "Effects of oral sodium cellulose phosphate therapy (5 g three times a day with meals for 4 days) on renal excretion of oxalate and on the crystallization of calcium oxalate in urine were examined in six patients with absorptive hypercalciuria on a constant metabolic dietary regimen. During treatment, urinary oxalate increased by 9-50 mg/day. However, urinary calcium decreased by 138-225 mg/day (50%-70%). Thus, the state of saturation of urine with respect to calcium oxalate decreased or did not change significantly. There was no consistent or significant change in the formation product ratio (limit of metastability) or in the crystal growth of calcium oxalate in urine.",

author = "Yasufumi Hayashi and Kaplan, {Roy A.} and Pak, {Charles Y C}",

note = "Funding Information: From the Section on Mineral Metabolism, Department of Internal Medicine, Southwestern Medical School, University of Texas Health Science Center at Dallas. Dallas, Texas. Received for publication March 12. 1975. This work was supported by grants from the USPHS (I-ROI-AM-16061 and I-MOI-RR40633). Dr. Kaplan is a postdoctoral fellow supported by USPHS grant 5-TOI-A M-05028. Reprint requests should be addressed to Dr. Charles Y. C. Pak. B-339, Southwestern Medical School, The University of Texas Health Science Center at Dallas. Dallas, Texas, 75235. 0 1975 by Grune & Stratton. fnc.",

year = "1975",

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doi = "10.1016/0026-0495(75)90065-7",

language = "English (US)",

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T1 - Effect of sodium cellulose phosphate therapy on crystallization of calcium oxalate in urine

AU - Hayashi, Yasufumi

AU - Kaplan, Roy A.

AU - Pak, Charles Y C

N1 - Funding Information: From the Section on Mineral Metabolism, Department of Internal Medicine, Southwestern Medical School, University of Texas Health Science Center at Dallas. Dallas, Texas. Received for publication March 12. 1975. This work was supported by grants from the USPHS (I-ROI-AM-16061 and I-MOI-RR40633). Dr. Kaplan is a postdoctoral fellow supported by USPHS grant 5-TOI-A M-05028. Reprint requests should be addressed to Dr. Charles Y. C. Pak. B-339, Southwestern Medical School, The University of Texas Health Science Center at Dallas. Dallas, Texas, 75235. 0 1975 by Grune & Stratton. fnc.

PY - 1975/11

Y1 - 1975/11

N2 - Effects of oral sodium cellulose phosphate therapy (5 g three times a day with meals for 4 days) on renal excretion of oxalate and on the crystallization of calcium oxalate in urine were examined in six patients with absorptive hypercalciuria on a constant metabolic dietary regimen. During treatment, urinary oxalate increased by 9-50 mg/day. However, urinary calcium decreased by 138-225 mg/day (50%-70%). Thus, the state of saturation of urine with respect to calcium oxalate decreased or did not change significantly. There was no consistent or significant change in the formation product ratio (limit of metastability) or in the crystal growth of calcium oxalate in urine.

AB - Effects of oral sodium cellulose phosphate therapy (5 g three times a day with meals for 4 days) on renal excretion of oxalate and on the crystallization of calcium oxalate in urine were examined in six patients with absorptive hypercalciuria on a constant metabolic dietary regimen. During treatment, urinary oxalate increased by 9-50 mg/day. However, urinary calcium decreased by 138-225 mg/day (50%-70%). Thus, the state of saturation of urine with respect to calcium oxalate decreased or did not change significantly. There was no consistent or significant change in the formation product ratio (limit of metastability) or in the crystal growth of calcium oxalate in urine.

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ER -

Effect of sodium cellulose phosphate therapy on crystallization of calcium oxalate in urine

Abstract

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