Effect of steatosis on liver signal and enhancement on multiphasic contrast-enhanced magnetic resonance imaging

Ali Pirasteh, Haley R. Clark, Endel A. Sorra, Ivan Pedrosa, Takeshi Yokoo

Research output: Contribution to journalArticlepeer-review

Abstract

Purpose: To investigate the effect of steatosis on liver signal and enhancement in multiphasic contrast-enhanced (MCE) MRI. Materials and methods: In this IRB-approved, HIPAA-compliant, retrospective, observational study, 1217 MCE abdominal MRIs performed during 2014 at a single institution were reviewed. Of these, 1085 were excluded, due to potential factors other than steatosis that may affect liver signal intensity and/or enhancement. In the remaining 132, liver fat fraction (FF) was calculated from the in- and opposed-phase 2D T1-weighted images. Liver signal intensity, absolute enhancement, and relative enhancement on fat-suppressed (Dixon method) 3D T1-weighted images before and after injection of gadobutrol (arterial, portal venous, and equilibrium phases) were plotted against co-localized FF values and the linear trend was evaluated by Pearson correlation coefficient (r). P values

Original languageEnglish (US)
Pages (from-to)1-7
Number of pages7
JournalAbdominal Radiology
DOIs
StateAccepted/In press - Apr 23 2016

Keywords

  • Contrast media
  • Fatty liver
  • Gadolinium
  • Liver steatosis
  • Magnetic resonance imaging

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Gastroenterology
  • Urology
  • Radiological and Ultrasound Technology

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