Effect of systane and optive on aqueous tear evaporation in patients with dry eye disease

Jadwiga C. Wojtowicz, Juan C. Arciniega, James P McCulley, Venkateswara Mootha

Research output: Contribution to journalArticle

7 Scopus citations

Abstract

Objective: To compare the effect on aqueous tear (AT) evaporation rate of Systane and Optive at 30 min postinstillation in patients with dry eye. Methods: In a crossover study of 20 patients with keratoconjunctivitis sicca, the evaporation rate of AT was measured. Evaporometry was used at two relative humidity (RH) ranges of 25% to 35% and 35% to 45%. The measurements were made at baseline (before the instillation of the study agent) and at 30 min after the instillation of 40 μL of either Systane or Optive per randomization assignment per visit with a 1-week interval between visits. Results: No significant effects on AT evaporation rates at both RHs were found between study agents. Conclusions: In our study, neither Systane nor Optive has a significant impact on AT evaporation at 30 min postinstillation in patients with dry eye.

Original languageEnglish (US)
Pages (from-to)358-360
Number of pages3
JournalEye and Contact Lens
Volume36
Issue number6
DOIs
StatePublished - Nov 1 2010

Keywords

  • Dry eye
  • Eye drop
  • Optive
  • Systane
  • Tear evaporation
  • Tear film

ASJC Scopus subject areas

  • Ophthalmology

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