Effect of T cell-derived lymphokines containing B cell differentiation factor(s) for IgG (BCDFγ) on γ-specific mRNA in murine B cells

S. Jones; Y. W. Chen; P. Isakson; J. Layton; E. Pure; C. Word; P. H. Krammer; P. Tucker; E. S. Vitetta

Effect of T cell-derived lymphokines containing B cell differentiation factor(s) for IgG (BCDFγ) on γ-specific mRNA in murine B cells

S. Jones, Y. W. Chen, P. Isakson, J. Layton, E. Pure, C. Word, P. H. Krammer, P. Tucker, E. S. Vitetta

Research output: Contribution to journal › Article › peer-review

Abstract

Cytoplasmic RNA was isolated from cells cultured with LPS and LPS plus a T cell-derived supernatant (SN) (PK 7.1) containing B cell differentiation factors. The steady state levels of isotype-specific mRNA were assessed by Northern blot analysis with γ-specific C(H)3 probes. It was demonstrated that the SN induces an increase in the level of mRNA for γ1 and a concomitant decrease in the levels of mRNA for γ2b and γ3.

Original language	English (US)
Pages (from-to)	3049-3051
Number of pages	3
Journal	Journal of Immunology
Volume	131
Issue number	6
State	Published - 1983

ASJC Scopus subject areas

Immunology and Allergy
Immunology

Cite this

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title = "Effect of T cell-derived lymphokines containing B cell differentiation factor(s) for IgG (BCDFγ) on γ-specific mRNA in murine B cells",

abstract = "Cytoplasmic RNA was isolated from cells cultured with LPS and LPS plus a T cell-derived supernatant (SN) (PK 7.1) containing B cell differentiation factors. The steady state levels of isotype-specific mRNA were assessed by Northern blot analysis with γ-specific C(H)3 probes. It was demonstrated that the SN induces an increase in the level of mRNA for γ1 and a concomitant decrease in the levels of mRNA for γ2b and γ3.",

author = "S. Jones and Chen, {Y. W.} and P. Isakson and J. Layton and E. Pure and C. Word and Krammer, {P. H.} and P. Tucker and Vitetta, {E. S.}",

year = "1983",

language = "English (US)",

volume = "131",

pages = "3049--3051",

journal = "Journal of Immunology",

issn = "0022-1767",

publisher = "American Association of Immunologists",

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TY - JOUR

T1 - Effect of T cell-derived lymphokines containing B cell differentiation factor(s) for IgG (BCDFγ) on γ-specific mRNA in murine B cells

AU - Jones, S.

AU - Chen, Y. W.

AU - Isakson, P.

AU - Layton, J.

AU - Pure, E.

AU - Word, C.

AU - Krammer, P. H.

AU - Tucker, P.

AU - Vitetta, E. S.

PY - 1983

Y1 - 1983

N2 - Cytoplasmic RNA was isolated from cells cultured with LPS and LPS plus a T cell-derived supernatant (SN) (PK 7.1) containing B cell differentiation factors. The steady state levels of isotype-specific mRNA were assessed by Northern blot analysis with γ-specific C(H)3 probes. It was demonstrated that the SN induces an increase in the level of mRNA for γ1 and a concomitant decrease in the levels of mRNA for γ2b and γ3.

AB - Cytoplasmic RNA was isolated from cells cultured with LPS and LPS plus a T cell-derived supernatant (SN) (PK 7.1) containing B cell differentiation factors. The steady state levels of isotype-specific mRNA were assessed by Northern blot analysis with γ-specific C(H)3 probes. It was demonstrated that the SN induces an increase in the level of mRNA for γ1 and a concomitant decrease in the levels of mRNA for γ2b and γ3.

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UR - http://www.scopus.com/inward/citedby.url?scp=0021081962&partnerID=8YFLogxK

M3 - Article

C2 - 6605997

AN - SCOPUS:0021081962

SN - 0022-1767

VL - 131

SP - 3049

EP - 3051

JO - Journal of Immunology

JF - Journal of Immunology

IS - 6

ER -

Effect of T cell-derived lymphokines containing B cell differentiation factor(s) for IgG (BCDFγ) on γ-specific mRNA in murine B cells

Abstract

ASJC Scopus subject areas

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