Effects of barodenervation on cardiovascular responses to static muscular contraction

T. G. Waldrop, J. H. Mitchell

Research output: Contribution to journalArticle

30 Scopus citations

Abstract

The purpose of this study was to measure blood flow to various tissues during static muscular contraction in anesthetized cats and to evaluate if the baroreflex modulates the cardiovascular responses to muscular contraction. Contraction of the hindlimb muscles induced by ventral root stimulation caused increases in arterial pressure (Δ 37.8 ± 5.5 mmHg) and heart rate (Δ 13.9 ± 3.1 beats/min). Increases in blood flow to the heart, working skeletal muscles, and selected areas of the central nervous system occurred during muscular contraction. Blood flow to visceral organs did not change during muscular contraction. Baroreceptor-denervated cats showed a greater rise in arterial pressure (Δ 55.5 ± 5.5 mm Hg) during muscular contraction than did the baroreceptor-intact cats. However, blood flow responses were similar in both groups. Thus the baroreceptor reflex modulates the pressor response without changing the alteration in blood flow during induced muscular contraction in anesthetized cats.

Original languageEnglish (US)
Pages (from-to)H710-H714
JournalAmerican Journal of Physiology - Heart and Circulatory Physiology
Volume18
Issue number4
DOIs
StatePublished - Jan 1 1985

ASJC Scopus subject areas

  • Physiology
  • Cardiology and Cardiovascular Medicine
  • Physiology (medical)

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