Effects of Chinese herbal medicines on DNA-synthesizing enzyme activities in mammary tumors of mice.

S. Sakamoto, R. Furuichi, M. Matsuda, H. Kudo, S. Suzuki, Y. Sugiura, K. Kuwa, M. Tajima, M. Matsubara, H. Namiki

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Sho-saiko-to (SST) and Juzen-taiho-to (JTT), Japanese modified Chinese herbal prescriptions, suppressed the activities of thymidylate synthetase and thymidine kinase involved in de novo and salvage pathways for pyrimidine nucleotide synthesis, respectively, in mammary tumors of SHN mice with the reduction of serum prolactin level. These results indicate that SST and JTT may have the antitumor effects on mammary tumors.

Original languageEnglish (US)
Pages (from-to)43-50
Number of pages8
JournalAmerican Journal of Chinese Medicine
Volume22
Issue number1
StatePublished - 1994

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Herbal Medicine
dTMP kinase
Pyrimidine Nucleotides
Breast Neoplasms
Thymidylate Synthase
Thymidine Kinase
DNA
Enzymes
Prolactin
Prescriptions
Serum
shosaiko-to
juzentaihoto

ASJC Scopus subject areas

  • Complementary and alternative medicine

Cite this

Sakamoto, S., Furuichi, R., Matsuda, M., Kudo, H., Suzuki, S., Sugiura, Y., ... Namiki, H. (1994). Effects of Chinese herbal medicines on DNA-synthesizing enzyme activities in mammary tumors of mice. American Journal of Chinese Medicine, 22(1), 43-50.

Effects of Chinese herbal medicines on DNA-synthesizing enzyme activities in mammary tumors of mice. / Sakamoto, S.; Furuichi, R.; Matsuda, M.; Kudo, H.; Suzuki, S.; Sugiura, Y.; Kuwa, K.; Tajima, M.; Matsubara, M.; Namiki, H.

In: American Journal of Chinese Medicine, Vol. 22, No. 1, 1994, p. 43-50.

Research output: Contribution to journalArticle

Sakamoto, S, Furuichi, R, Matsuda, M, Kudo, H, Suzuki, S, Sugiura, Y, Kuwa, K, Tajima, M, Matsubara, M & Namiki, H 1994, 'Effects of Chinese herbal medicines on DNA-synthesizing enzyme activities in mammary tumors of mice.', American Journal of Chinese Medicine, vol. 22, no. 1, pp. 43-50.
Sakamoto, S. ; Furuichi, R. ; Matsuda, M. ; Kudo, H. ; Suzuki, S. ; Sugiura, Y. ; Kuwa, K. ; Tajima, M. ; Matsubara, M. ; Namiki, H. / Effects of Chinese herbal medicines on DNA-synthesizing enzyme activities in mammary tumors of mice. In: American Journal of Chinese Medicine. 1994 ; Vol. 22, No. 1. pp. 43-50.
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AU - Sugiura, Y.

AU - Kuwa, K.

AU - Tajima, M.

AU - Matsubara, M.

AU - Namiki, H.

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