Effects of crystalline nicotinic acid-induced hepatic dysfunction on serum low-density lipoprotein cholesterol and lecithin cholesteryl acyl transferase

Federico Tatò, Gloria L Vega, Scott M Grundy

Research output: Contribution to journalArticle

38 Scopus citations


Marked lowering of plasma total and low-density lipoproteins cholesterol levels that occur during treatment of dyslipidemia with pharmacologic doses of nicotinic acid result from hepatotoxicity. Therefore, a marked reduction in low-density lipoprotein may suggest generalized liver toxicity and drug treatment should be discontinued.

Original languageEnglish (US)
Pages (from-to)805-807
Number of pages3
JournalAmerican Journal of Cardiology
Issue number6
Publication statusPublished - Mar 15 1998


ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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