Effects of in vivo cocaine administration on human platelet aggregation

Christian M. Heesch; Brian H. Negus; Manfred Steiner; Richard W. Snyder; Donald D. McIntire; Paul A. Grayburn Md; Joy Ashcraft; José A. Hernández; Eric J. Eichhorn

doi:10.1016/S0002-9149(96)00267-6

Effects of in vivo cocaine administration on human platelet aggregation

Christian M. Heesch, Brian H. Negus, Manfred Steiner, Richard W. Snyder, Donald D. McIntire, Paul A. Grayburn Md, Joy Ashcraft, José A. Hernández, Eric J. Eichhorn

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

Abstract

To evaluate whether cocaine administration to human volunteers in vivo increases platelet aggregation, 12 healthy male volunteers were studied twice in a prospective, double-blinded fashion. There was a decrease in aggregation following cocaine exposure compared to placebo, which was most prominent at high doses of adenosine diphosphate.

Original language	English (US)
Pages (from-to)	237-239
Number of pages	3
Journal	American Journal of Cardiology
Volume	78
Issue number	2
DOIs	https://doi.org/10.1016/S0002-9149(96)00267-6
State	Published - Jul 15 1996

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

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title = "Effects of in vivo cocaine administration on human platelet aggregation",

abstract = "To evaluate whether cocaine administration to human volunteers in vivo increases platelet aggregation, 12 healthy male volunteers were studied twice in a prospective, double-blinded fashion. There was a decrease in aggregation following cocaine exposure compared to placebo, which was most prominent at high doses of adenosine diphosphate.",

author = "Heesch, {Christian M.} and Negus, {Brian H.} and Manfred Steiner and Snyder, {Richard W.} and McIntire, {Donald D.} and {Grayburn Md}, {Paul A.} and Joy Ashcraft and Hern{\'a}ndez, {Jos{\'e} A.} and Eichhorn, {Eric J.}",

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AU - Heesch, Christian M.

AU - Negus, Brian H.

AU - Steiner, Manfred

AU - Snyder, Richard W.

AU - McIntire, Donald D.

AU - Grayburn Md, Paul A.

AU - Ashcraft, Joy

AU - Hernández, José A.

AU - Eichhorn, Eric J.

PY - 1996/7/15

Y1 - 1996/7/15

N2 - To evaluate whether cocaine administration to human volunteers in vivo increases platelet aggregation, 12 healthy male volunteers were studied twice in a prospective, double-blinded fashion. There was a decrease in aggregation following cocaine exposure compared to placebo, which was most prominent at high doses of adenosine diphosphate.

AB - To evaluate whether cocaine administration to human volunteers in vivo increases platelet aggregation, 12 healthy male volunteers were studied twice in a prospective, double-blinded fashion. There was a decrease in aggregation following cocaine exposure compared to placebo, which was most prominent at high doses of adenosine diphosphate.

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Effects of in vivo cocaine administration on human platelet aggregation

Abstract

ASJC Scopus subject areas

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