Effects of in vivo cocaine administration on human platelet aggregation

Christian M. Heesch, Brian H. Negus, Manfred Steiner, Richard W. Snyder, Donald D. McIntire, Paul A. Grayburn Md, Joy Ashcraft, José A. Hernández, Eric J. Eichhorn

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

To evaluate whether cocaine administration to human volunteers in vivo increases platelet aggregation, 12 healthy male volunteers were studied twice in a prospective, double-blinded fashion. There was a decrease in aggregation following cocaine exposure compared to placebo, which was most prominent at high doses of adenosine diphosphate.

Original languageEnglish (US)
Pages (from-to)237-239
Number of pages3
JournalAmerican Journal of Cardiology
Volume78
Issue number2
DOIs
StatePublished - Jul 15 1996

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Platelet Aggregation
Cocaine
Adenosine Diphosphate
Volunteers
Healthy Volunteers
Placebos

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Heesch, C. M., Negus, B. H., Steiner, M., Snyder, R. W., McIntire, D. D., Grayburn Md, P. A., ... Eichhorn, E. J. (1996). Effects of in vivo cocaine administration on human platelet aggregation. American Journal of Cardiology, 78(2), 237-239. https://doi.org/10.1016/S0002-9149(96)00267-6

Effects of in vivo cocaine administration on human platelet aggregation. / Heesch, Christian M.; Negus, Brian H.; Steiner, Manfred; Snyder, Richard W.; McIntire, Donald D.; Grayburn Md, Paul A.; Ashcraft, Joy; Hernández, José A.; Eichhorn, Eric J.

In: American Journal of Cardiology, Vol. 78, No. 2, 15.07.1996, p. 237-239.

Research output: Contribution to journalArticle

Heesch, CM, Negus, BH, Steiner, M, Snyder, RW, McIntire, DD, Grayburn Md, PA, Ashcraft, J, Hernández, JA & Eichhorn, EJ 1996, 'Effects of in vivo cocaine administration on human platelet aggregation', American Journal of Cardiology, vol. 78, no. 2, pp. 237-239. https://doi.org/10.1016/S0002-9149(96)00267-6
Heesch, Christian M. ; Negus, Brian H. ; Steiner, Manfred ; Snyder, Richard W. ; McIntire, Donald D. ; Grayburn Md, Paul A. ; Ashcraft, Joy ; Hernández, José A. ; Eichhorn, Eric J. / Effects of in vivo cocaine administration on human platelet aggregation. In: American Journal of Cardiology. 1996 ; Vol. 78, No. 2. pp. 237-239.
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