Effects of lower body positive pressure on muscle sympathetic nerve activity.

Qi Fu, Y. Sugiyama, A. Kamiya, A. S. Shamsuzzaman, T. Mano

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Citation (Scopus)

Abstract

To elucidate the role of vasomotor sympathetic nerve activity response to lower-body positive pressure (LBPP), muscle sympathetic nerve activity (MSNA) along with blood pressure, electrocardiogram, transthoracic impedance and echocardiogram were recorded in ten healthy young men at 10, 20 and 30 mmHg LBPP in the supine position. We found that MSNA was suppressed (27%) at both 10 and 20 mmHg LBPP but tended to increase at 30 mmHg LBPP. Mean arterial pressure (11%) and total peripheral resistance (36%) increased despite a tendency toward decreased stroke volume and cardiac output at 30 mmHg LBPP. Heart rate remained unchanged. The left atrial dimension significantly increased during 10-30 mmHg LBPP, indicating an increase in cardiac filling. These results suggest that LBPP at levels less than 20 mmHg suppressed MSNA by the translocation of blood from the lower body to the thorax, thus stimulating the cardiopulmonary baroreceptors which in turn inhibited vasomotor sympathetic nerve activity. However, LBPP at 30 mmHg tended to enhance MSNA through the activation of intramuscular (pressure-sensitive) receptors which could counteract the inhibitory effect of cardiopulmonary baroreflexes on MSNA.

Original languageEnglish (US)
Title of host publicationEnvironmental medicine : annual report of the Research Institute of Environmental Medicine, Nagoya University
Pages76-78
Number of pages3
Volume42
Edition1
StatePublished - 1998

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Pressure
Muscles
Impedance Cardiography
Pressoreceptors
Baroreflex
Supine Position
Cardiac Output
Vascular Resistance
Stroke Volume
Arterial Pressure
Electrocardiography
Thorax
Heart Rate
Blood Pressure

Cite this

Fu, Q., Sugiyama, Y., Kamiya, A., Shamsuzzaman, A. S., & Mano, T. (1998). Effects of lower body positive pressure on muscle sympathetic nerve activity. In Environmental medicine : annual report of the Research Institute of Environmental Medicine, Nagoya University (1 ed., Vol. 42, pp. 76-78)

Effects of lower body positive pressure on muscle sympathetic nerve activity. / Fu, Qi; Sugiyama, Y.; Kamiya, A.; Shamsuzzaman, A. S.; Mano, T.

Environmental medicine : annual report of the Research Institute of Environmental Medicine, Nagoya University. Vol. 42 1. ed. 1998. p. 76-78.

Research output: Chapter in Book/Report/Conference proceedingChapter

Fu, Q, Sugiyama, Y, Kamiya, A, Shamsuzzaman, AS & Mano, T 1998, Effects of lower body positive pressure on muscle sympathetic nerve activity. in Environmental medicine : annual report of the Research Institute of Environmental Medicine, Nagoya University. 1 edn, vol. 42, pp. 76-78.
Fu Q, Sugiyama Y, Kamiya A, Shamsuzzaman AS, Mano T. Effects of lower body positive pressure on muscle sympathetic nerve activity. In Environmental medicine : annual report of the Research Institute of Environmental Medicine, Nagoya University. 1 ed. Vol. 42. 1998. p. 76-78
Fu, Qi ; Sugiyama, Y. ; Kamiya, A. ; Shamsuzzaman, A. S. ; Mano, T. / Effects of lower body positive pressure on muscle sympathetic nerve activity. Environmental medicine : annual report of the Research Institute of Environmental Medicine, Nagoya University. Vol. 42 1. ed. 1998. pp. 76-78
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