Effects of naloxone on the cardiovascular responses to muscular contraction in decerebrate cats

Tony G. Waldrop, Gary A. Iwamoto

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

The cardiovascular response to muscular contraction induced by ventral root (L7 and S1) stimulation were studied in unanesthetized decerebrate cats before and after the administration of the opiate antagonist naloxone. Intravenous naloxone (1.0-2.0 mg/kg) did not alter the heart rate or arterial pressure responses to either tetanic or repeated twitch contractions. However, naloxone did increase resting arterial pressure.

Original languageEnglish (US)
Pages (from-to)152-156
Number of pages5
JournalBrain Research
Volume322
Issue number1
DOIs
StatePublished - Nov 19 1984

Fingerprint

Naloxone
Muscle Contraction
Cats
Opiate Alkaloids
Arterial Pressure
Spinal Nerve Roots
Heart Rate

Keywords

  • arterial pressure
  • cat
  • endogenous opiates
  • heart rate
  • muscular contraction
  • naloxone

ASJC Scopus subject areas

  • Developmental Biology
  • Molecular Biology
  • Clinical Neurology
  • Neuroscience(all)

Cite this

Effects of naloxone on the cardiovascular responses to muscular contraction in decerebrate cats. / Waldrop, Tony G.; Iwamoto, Gary A.

In: Brain Research, Vol. 322, No. 1, 19.11.1984, p. 152-156.

Research output: Contribution to journalArticle

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