Effects of naloxone on the cardiovascular responses to muscular contraction in decerebrate cats

Tony G. Waldrop, Gary A. Iwamoto

Research output: Contribution to journalArticle

9 Scopus citations

Abstract

The cardiovascular response to muscular contraction induced by ventral root (L7 and S1) stimulation were studied in unanesthetized decerebrate cats before and after the administration of the opiate antagonist naloxone. Intravenous naloxone (1.0-2.0 mg/kg) did not alter the heart rate or arterial pressure responses to either tetanic or repeated twitch contractions. However, naloxone did increase resting arterial pressure.

Original languageEnglish (US)
Pages (from-to)152-156
Number of pages5
JournalBrain Research
Volume322
Issue number1
DOIs
StatePublished - Nov 19 1984

Keywords

  • arterial pressure
  • cat
  • endogenous opiates
  • heart rate
  • muscular contraction
  • naloxone

ASJC Scopus subject areas

  • Neuroscience(all)
  • Molecular Biology
  • Clinical Neurology
  • Developmental Biology

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