Effects of steroid therapy on membranous nephropathy

Takashi Takei, Asuka Aoki, Aya Eguchi, Ari Shimizu, Yuko Iwasa, Yukari Asamiya, Nami Matsuda, Hidekazu Sugiura, Mitsuyo Itabashi, Satsuki Shirota, Misao Tsukada, Takumu Yoshida, Keiko Uchida, Ken Tsuchiya, Kosaku Nitta

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Background : Although membranous nephropathy is a common cause of nephrotic syndrome in adults, its treatment remains under debate. Methods : To clarify the effects of steroid therapy, the data of 51 Japanese adult patients with idiopathic membranous nephropathy who received treatment at our department were analyzed retrospectively. We divided the patients with nephrotic syndrome and a serum creatinine level <1.7 mg/dL, into two groups : the steroid therapy group (n=20) and the non-steroid therapy group (n=7), and compared the clinical characteristics between the two groups. Results : Significantly decreased proteinuria levels (p<0.05) after 2 and 5 years were observed in the steroid therapy group as compared to the non-steroid therapy group. There was no significant difference in the serum creatinine levels after 2 and 5 years between the steroid therapy group and the non-steroid therapy group. Conclusion : Steroid therapy in idiopathic membranous nephropathy showed good efficacy in patients with nephrotic syndrome.

Original languageEnglish (US)
Pages (from-to)597-601
Number of pages5
JournalJapanese Journal of Nephrology
Volume50
Issue number5
StatePublished - 2008

Fingerprint

Membranous Glomerulonephritis
Group Psychotherapy
Steroids
Nephrotic Syndrome
Creatinine
Therapeutics
Serum
Proteinuria

Keywords

  • Membranous nephropathy
  • Nephrotic syndrome
  • Steroid therapy

ASJC Scopus subject areas

  • Nephrology

Cite this

Takei, T., Aoki, A., Eguchi, A., Shimizu, A., Iwasa, Y., Asamiya, Y., ... Nitta, K. (2008). Effects of steroid therapy on membranous nephropathy. Japanese Journal of Nephrology, 50(5), 597-601.

Effects of steroid therapy on membranous nephropathy. / Takei, Takashi; Aoki, Asuka; Eguchi, Aya; Shimizu, Ari; Iwasa, Yuko; Asamiya, Yukari; Matsuda, Nami; Sugiura, Hidekazu; Itabashi, Mitsuyo; Shirota, Satsuki; Tsukada, Misao; Yoshida, Takumu; Uchida, Keiko; Tsuchiya, Ken; Nitta, Kosaku.

In: Japanese Journal of Nephrology, Vol. 50, No. 5, 2008, p. 597-601.

Research output: Contribution to journalArticle

Takei, T, Aoki, A, Eguchi, A, Shimizu, A, Iwasa, Y, Asamiya, Y, Matsuda, N, Sugiura, H, Itabashi, M, Shirota, S, Tsukada, M, Yoshida, T, Uchida, K, Tsuchiya, K & Nitta, K 2008, 'Effects of steroid therapy on membranous nephropathy', Japanese Journal of Nephrology, vol. 50, no. 5, pp. 597-601.
Takei T, Aoki A, Eguchi A, Shimizu A, Iwasa Y, Asamiya Y et al. Effects of steroid therapy on membranous nephropathy. Japanese Journal of Nephrology. 2008;50(5):597-601.
Takei, Takashi ; Aoki, Asuka ; Eguchi, Aya ; Shimizu, Ari ; Iwasa, Yuko ; Asamiya, Yukari ; Matsuda, Nami ; Sugiura, Hidekazu ; Itabashi, Mitsuyo ; Shirota, Satsuki ; Tsukada, Misao ; Yoshida, Takumu ; Uchida, Keiko ; Tsuchiya, Ken ; Nitta, Kosaku. / Effects of steroid therapy on membranous nephropathy. In: Japanese Journal of Nephrology. 2008 ; Vol. 50, No. 5. pp. 597-601.
@article{0144527d638d43c09fae384f9fa1bcdb,
title = "Effects of steroid therapy on membranous nephropathy",
abstract = "Background : Although membranous nephropathy is a common cause of nephrotic syndrome in adults, its treatment remains under debate. Methods : To clarify the effects of steroid therapy, the data of 51 Japanese adult patients with idiopathic membranous nephropathy who received treatment at our department were analyzed retrospectively. We divided the patients with nephrotic syndrome and a serum creatinine level <1.7 mg/dL, into two groups : the steroid therapy group (n=20) and the non-steroid therapy group (n=7), and compared the clinical characteristics between the two groups. Results : Significantly decreased proteinuria levels (p<0.05) after 2 and 5 years were observed in the steroid therapy group as compared to the non-steroid therapy group. There was no significant difference in the serum creatinine levels after 2 and 5 years between the steroid therapy group and the non-steroid therapy group. Conclusion : Steroid therapy in idiopathic membranous nephropathy showed good efficacy in patients with nephrotic syndrome.",
keywords = "Membranous nephropathy, Nephrotic syndrome, Steroid therapy",
author = "Takashi Takei and Asuka Aoki and Aya Eguchi and Ari Shimizu and Yuko Iwasa and Yukari Asamiya and Nami Matsuda and Hidekazu Sugiura and Mitsuyo Itabashi and Satsuki Shirota and Misao Tsukada and Takumu Yoshida and Keiko Uchida and Ken Tsuchiya and Kosaku Nitta",
year = "2008",
language = "English (US)",
volume = "50",
pages = "597--601",
journal = "Nihon Jinzo Gakkai shi",
issn = "0385-2385",
publisher = "Japanese Society of Nephrology",
number = "5",

}

TY - JOUR

T1 - Effects of steroid therapy on membranous nephropathy

AU - Takei, Takashi

AU - Aoki, Asuka

AU - Eguchi, Aya

AU - Shimizu, Ari

AU - Iwasa, Yuko

AU - Asamiya, Yukari

AU - Matsuda, Nami

AU - Sugiura, Hidekazu

AU - Itabashi, Mitsuyo

AU - Shirota, Satsuki

AU - Tsukada, Misao

AU - Yoshida, Takumu

AU - Uchida, Keiko

AU - Tsuchiya, Ken

AU - Nitta, Kosaku

PY - 2008

Y1 - 2008

N2 - Background : Although membranous nephropathy is a common cause of nephrotic syndrome in adults, its treatment remains under debate. Methods : To clarify the effects of steroid therapy, the data of 51 Japanese adult patients with idiopathic membranous nephropathy who received treatment at our department were analyzed retrospectively. We divided the patients with nephrotic syndrome and a serum creatinine level <1.7 mg/dL, into two groups : the steroid therapy group (n=20) and the non-steroid therapy group (n=7), and compared the clinical characteristics between the two groups. Results : Significantly decreased proteinuria levels (p<0.05) after 2 and 5 years were observed in the steroid therapy group as compared to the non-steroid therapy group. There was no significant difference in the serum creatinine levels after 2 and 5 years between the steroid therapy group and the non-steroid therapy group. Conclusion : Steroid therapy in idiopathic membranous nephropathy showed good efficacy in patients with nephrotic syndrome.

AB - Background : Although membranous nephropathy is a common cause of nephrotic syndrome in adults, its treatment remains under debate. Methods : To clarify the effects of steroid therapy, the data of 51 Japanese adult patients with idiopathic membranous nephropathy who received treatment at our department were analyzed retrospectively. We divided the patients with nephrotic syndrome and a serum creatinine level <1.7 mg/dL, into two groups : the steroid therapy group (n=20) and the non-steroid therapy group (n=7), and compared the clinical characteristics between the two groups. Results : Significantly decreased proteinuria levels (p<0.05) after 2 and 5 years were observed in the steroid therapy group as compared to the non-steroid therapy group. There was no significant difference in the serum creatinine levels after 2 and 5 years between the steroid therapy group and the non-steroid therapy group. Conclusion : Steroid therapy in idiopathic membranous nephropathy showed good efficacy in patients with nephrotic syndrome.

KW - Membranous nephropathy

KW - Nephrotic syndrome

KW - Steroid therapy

UR - http://www.scopus.com/inward/record.url?scp=51149114029&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=51149114029&partnerID=8YFLogxK

M3 - Article

VL - 50

SP - 597

EP - 601

JO - Nihon Jinzo Gakkai shi

JF - Nihon Jinzo Gakkai shi

SN - 0385-2385

IS - 5

ER -